Quantitative fluctuation of a new Bayesian penalized-likelihood reconstruction algorithm in Ga-68 DOTATOC PET/CT.

Conclusions: Although all quantitative parameters of PL method had strong correlation with those of conventional OSEM, significant differences in SUV parameters between the two methods should be noted for quantification of Ga-68 DOTATOC PET. Although parameters fluctuate with β values, SUVpeak could be a reproducible parameter because of the smallest variance among different β values. Quantitative parameters (mean±SD)PLOSEMpSUVmax24.1±21.322.1±20.7<0.01SUVmean14.4±13.313.1±12.8<0.01SUVpeak17.9±17.616.8±17.2<0.01MTV11.5±18.012.7±15.9>0.1TLU145.1±203.2140.0±182.8>0.1Coefficient of variation among β=300-600 (mean±SD)SUVmax0.062±0.044SUVmean0.056±0.036SUVpeak0.025±0.018MTV0.114±0.155TLU0.079±0.13
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Technical Advances in Clinical Assessment of Soild Tumors Source Type: research