Dissecting the heart/brain interaction in post-infarct myocardial inflammation by whole body translocator protein (TSPO) imaging

Conclusions: Acute post-infarct myocardial inflammation and progressive contractile dysfunction are associated with neuroinflammation. Preventative treatment with enalapril protects the heart and brain from acute inflammation, and lowers cardiac remodeling. The chronic effect of enalapril on neuroinflammation and its importance for development of cognitive impairment require further investigation.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Cardiovascular Molecular Imaging: Innervation and Inflammation Source Type: research