Antimicrobial and anticancer activities of silver nanoparticles synthesized from the root hair extract of Phoenix dactylifera.

Antimicrobial and anticancer activities of silver nanoparticles synthesized from the root hair extract of Phoenix dactylifera. Mater Sci Eng C Mater Biol Appl. 2018 Aug 01;89:429-443 Authors: Oves M, Aslam M, Rauf MA, Qayyum S, Qari HA, Khan MS, Alam MZ, Tabrez S, Pugazhendhi A, Ismail IMI Abstract There is a continuous rise in the rate of medicine consumption because of the development of drug resistance by microbial pathogens. In the last one decade, silver nanoparticles (AgNPs) have become a remarkable choice for the development of new drugs due to their excellent broad-spectrum antimicrobial activity. In the current piece of work, we have synthesized AgNPs from the root extract of Phoenix dactylifera to test their antimicrobial and anti-cancer potential. UV-visible spectra showed the surface plasmon resonance peak at 420 nm λmax corresponding to the formation of silver nanoparticles, FTIR spectra further confirmed the involvement of biological moieties in AgNPs synthesis. Moreover, XRD analysis showed the crystalline nature of AgNPs and predicted the crystallite size of 15 to 40 nm. Electron microscopy analyses confirmed their spherical shape. In addition, synthesized AgNPs was also found to control the growth of C. albicans and E. coli on solid nutrient medium with 20 and 22 mm zone of inhibition, respectively. The 100% potency at 40 μg/ml AgNPs concentration was observed against E. coli and C. albicans after 4 h and...
Source: Appl Human Sci - Category: Physiology Authors: Tags: Mater Sci Eng C Mater Biol Appl Source Type: research