FG-4592 Accelerates Cutaneous Wound Healing by Epidermal Stem Cell Activation via HIF-1 α Stabilization
Conclusion: This study demonstrated that both hypoxia and exogenous FG-4592 improve EpSC proliferation and motility by stabilizing HIF-1 α, and its results suggest that HIF-1α is an important target through which wound healing can be accelerated and that FG-4592 is a promising new drug for wound repair.Cell Physiol Biochem 2018;46:2460 –2470
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research
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