SIOPE - Brain tumor group consensus guideline on craniospinal target volume delineation for high-precision radiotherapy.

CONCLUSION: This consensus guideline has the potential to improve consistency of craniospinal TV delineation in an era of high-precision radiotherapy. This proposal will be incorporated in the RTQA guidelines of future SIOPE-BTG trials using CSI. PMID: 29729847 [PubMed - as supplied by publisher]
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research

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ConclusionsThe phantom data show the validity of our fast distortion correction algorithm. Patient-specific data are acquired in
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
Authors: Suo F, Zhong B, Lu F, Dong Z Abstract Glioma is the most aggressive brain tumor and is associated with a high mortality rate. The aim of the present study was to explore the association between matrix metalloproteinase 2 (MMP-2) and ephrin type-A receptor 2 (EphA2) expression in glioma cells, and to investigate the contribution of magnetic resonance imaging (MRI) in glioma classification. A total of 43 patients with pathologically confirmed glioma were divided into two groups as follows: Low-grade (grades I and II; n=21) and high-grade (grades IV and IV; n=22). Subsequently, immunohistochemistry staining w...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
AbstractPrimary central nervous system lymphomas (PCNSLs) are typically intraparenchymal. A subset of PCNSLs predominantly arises in the ventricles, with minimal parenchymal involvement. We review the clinical, radiological, and pathological features of ventricle-predominant PCNSLs (VP-PCNSLs) in 40 previously reported cases and report 5 additional cases. Including all cases of VP-PCNSLs (n = 45), 38% were diffuse large B-cell lymphomas (DLBCL), 11% were Burkitt lymphomas, 7% were MALT lymphomas, 4% were T-cell lymphomas, and 40% were lymphomas, not otherwise classified. VP-PCNSLs show rapid clinical progress...
Source: Brain Tumor Pathology - Category: Neurology Source Type: research
CONCLUSION: A multivariate prediction model created using blood flow, vascular permeability, and glycometabolism parameters can predict the extent of hypoxia in FMISO-positive areas in patients with brain tumors. PMID: 31611541 [PubMed - as supplied by publisher]
Source: Magnetic Resonance in Medical Sciences : MRMS - Category: Radiology Authors: Tags: Magn Reson Med Sci Source Type: research
Publication date: Available online 24 September 2019Source: NeuroImageAuthor(s): Luciano Simone, Luca Fornia, Luca Viganò, Fabio Sambataro, Marco Rossi, Antonella Leonetti, Guglielmo Puglisi, Henrietta Howells, Andrea Bellacicca, Lorenzo Bello, Gabriella CerriThe development of awake intraoperative brain-mapping procedures for resection of brain tumors is of growing interest in neuroscience, because it enables direct testing of brain tissue, previously only possible in non-human primates. In a recent study performed in this setting specific effects can be induced by direct electrical stimulation on different sectors...
Source: NeuroImage - Category: Neuroscience Source Type: research
Researchers from the University of Strathclyde have developed a blood test that could help to accelerate the diagnosis of brain cancer. The technology uses infrared light to produce a "bio-signature" of a blood sample and applies artificial intelligence to check for the signs of cancer. This research is being commercialized by ClinSpec Diagnostics Ltd, a company spun out from the university in February 2019. The work has now been published in the journal Nature Communications, and also involved clinicians at the Western General Hospital in Edinburgh, the University of Liverpool and the Walton NHS Foundation Trust...
Source: MDDI - Category: Medical Devices Authors: Tags: IVD Digital Health Source Type: news
Abstract13N-Ammonia (13N-NH3) is widely used positron emission tomography/computed tomography (PET/CT) radiotracer for the measurement of myocardial blood perfusion; the possible role of13N-NH3 PET or PET/CT in oncological disease is not yet clear. Aim of this review is to evaluate the diagnostic performances of13N-NH3 PET in this field. A comprehensive computer literature search of the PubMed/MEDLINE, Scopus, and Embase databases was conducted including articles up to June 2019. Eighteen articles were finally included in the review. From the analyses of the selected studies, the following main findings could be drawn: (1)...
Source: Japanese Journal of Radiology - Category: Radiology Source Type: research
Author Katie Smith, 33, from Stourbridge, West Midlands, won Lorraine's Top Tales prize in 2016. Appearing on the show today, she revealed she lives her life 'three months at a time' between scans.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
How can you have a moonshot trying to cure cancer and not mention people dying of cancer?I believed the narrative that is pushed on women, that if you check your breasts and if you catch it early, you’re fine.ide class="right-rail__container right-rail__container--ad"> Lianne Kraemer had been living with metastatic breast cancer for more than a year when I met her in December 2017 at the Henry B. González Convention Center in San Antonio. Throughout the week, more than 7,000 doctors, scientists and pharmaceutical-company representatives would descend on the city for the country’s most impor...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Breast Cancer health Source Type: news
ConclusionsThese findings provide evidence from molecular, cellular, and physiological levels that strongly suggest that CC12 is a promising small-molecule agent for human GBM.Legal entity responsible for the studyThe author.FundingHas not received any funding.DisclosureThe author has declared no conflicts of interest.
Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research
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