SIOPE - Brain tumor group consensus guideline on craniospinal target volume delineation for high-precision radiotherapy.
CONCLUSION: This consensus guideline has the potential to improve consistency of craniospinal TV delineation in an era of high-precision radiotherapy. This proposal will be incorporated in the RTQA guidelines of future SIOPE-BTG trials using CSI. PMID: 29729847 [PubMed - as supplied by publisher]
Conclusions: This study demonstrated that a noninvasive imaging strategy enables rapid quantification of receptor availability in response to therapy, a capability that could be leveraged in preclinical drug development, patient stratification, and treatment monitoring.
ConclusionspcPET tracers present potential utility in the differential diagnosis, estimation of prognosis, evaluation of recurrence and treatment planning in patients with glioma. These radiotracers may hold a complementary role in conjunction with advanced MRI techniques in the non-invasive grading of gliomas.
Conclusion: The integrated robotic system can place NBTU ablator at a desired target location in porcine brain and monitor the ablation in realtime via magnetic resonance thermal imaging (MRTI). Significance: Further optimization of this system could result in a clinically viable syste- for use in human trials for various diagnostic or therapeutic neurosurgical interventions.
CONCLUSION: We observed a correlation between PoETV and OS. This imaging biomarker may help predict the OS of patients with GBM. PMID: 32938221 [PubMed - as supplied by publisher]
Conclusion: Intraoperative CT scan is safe and logistically and financially advantageous. It provides versatile benefits allowing for safe and maximal surgery, requiring minimum changes to an existing neurosurgical setup. Intraoperative CT scan provides clinical benefit in technically difficult cases and has a smooth workflow. PMID: 32905376 [PubMed]
Extraneural metastases of primary brain tumors are rare. Here, we provided a case of a 19-year-old man presenting with 2 intra-abdominal masses, who had a history of intracranial germ cell tumors and a ventriculoperitoneal shunt implanted in order to alleviate obstructive hydrocephalus. The intra-abdominal lesions showed intense FDG uptake and were confirmed to be germ cell tumors by postoperative histopathology. 18F-FDG PET scan could be useful in monitoring metastases of intracranial germ cell tumors via ventriculoperitoneal shunt.
The involvement of the central nervous system (CNS) in Hodgkin lymphoma (HL) has been rarely reported, especially in its primary isolated form. Herein, we present a case of a 33-year-old woman, who received immunosuppressive treatment due to ulcerative colitis (at the beginning azathioprine and sulfasalazine, changed to mesalazine), with repetitive episodes of loss of consciousness for a few weeks and with no other symptoms. Magnetic resonance imaging scans of the head revealed a tumor in the lateral part of the left temporal lobe and in the cerebellum. Moreover, a subsequent computed tomographic scan of the chest revealed...
PET using O-(2-18F-fluoroethyl)-l-tyrosine (18F-FET) is useful to detect residual tumor tissue after glioma resection. Recent animal experiments detected reactive changes in 18F-FET uptake at the rim of the resection cavity within the first 2 wk after resection of gliomas. In the present study, we evaluated pre- and postoperative 18F-FET PET scans of glioma patients with particular emphasis on the identification of reactive changes after surgery. Methods: Forty-three patients with cerebral gliomas (9 low-grade, 34 high-grade; 9 primary tumors, 34 recurrent tumors) who had preoperative (time before surgery: median, 23 d; ra...
In conclusion, our results confirm pr evious data that depression affects more than ¼ of patients with primary brain tumors, it is largely independent of tumor characteristics and is associated with shorter survival in patients with recurrent malignant gliomas. On PET imaging, higher tryptophan metabolism in the frontal cortex and thal amus was found in those with brain tumor-associated depression and supports the role of dysregulated tryptophan/kynurenine metabolism in this condition.
AbstractIn recent times, researchers showed huge interest in machine learning approaches that attempts to develop the information representations via computational modules. Past decade gained momentum by deep learning approaches and their potential of enhancing the performance for numerous automation operations with superior future research applications. The novelties in medical image processing initialized the unique perspective to diagnose the human body with superior resolution and enhanced accuracy. This paper offers a comprehensive work on existing methodologies that attain optimum results in their respective domains....