Integrative kinome profiling identifies mTORC1/2 inhibition as treatment strategy in ovarian clear cell carcinoma.

CONCLUSIONS: These results propose mTORC1/2 inhibition as an effective treatment strategy in OCCC.
PMID: 29685880 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - April 23, 2018 Category: Cancer & Oncology Authors: Caumanns JJ, Berns K, Wisman GBA, Fehrmann RSN, Tomar T, Klip H, Meersma GJ, Hijmans EM, Gennissen A, Duiker EW, Weening D, Itamochi H, Kluin RJ, Reyners AKL, Birrer MJ, Salvesen HB, Vergote I, Van Nieuwenhuysen E, Brenton JD, Braicu EI, Kupryjanczyk J, S Tags: Clin Cancer Res Source Type: research