Molecular epidemiology of human adenovirus infections in Denmark, 2011-2016

Human adenoviruses (HAdVs) consist of seven different species (A to G) subdivided into 67 HAdV types [1,2]. HAdV typing is performed by PCR amplification and sequencing of a hypervariable region of the hexon gene, coding for one of three HAdV capsid proteins. HAdV can cause a wide range of diseases, namely febrile respiratory tract infections, conjunctivitis, diarrhoea and more rarely haemorrhagic cystitis and meningitis. Recent studies identified HAdV among 6% to 20% of hospitalized or emergency room admitted children [3 –6] presenting with lower respiratory tract infections and 10% and 23% of children admitted with acute gastroenteritis [7,8].

Source: Journal of Clinical Virology - April 20, 2018 Category: Virology Authors: C éline Barnadas, Dennis Jelsbak Schmidt, Thea K. Fischer, Jannik Fonager Source Type: research