Synthesis and Antibacterial Activity Against MRSA of Pleuromutilin Derivatives Possessing a Mercaptoethylamine Linker.

CONCLUSION: It was found that there is a reasonable correlation between the binding free energy and the antibacterial activity.
PMID: 29663895 [PubMed - as supplied by publisher]

Source: Medicinal Chemistry - April 16, 2018 Category: Chemistry Authors: Zhang ZS, Huang YZ, Luo J, Wang BF, Jin Z, Liu YH, Tang YZ Tags: Med Chem Source Type: research