Antimicrobial Potential of Polyphenols: An Update on Alternative for Combating Antimicrobial Resistance
Med Chem. 2024 Apr 5. doi: 10.2174/0115734064277579240328142639. Online ahead of print.ABSTRACTThe last decade has encountered an increasing demand for plant-based natural antibiotics. This demand has led to more research-based investigations for natural sources of antimicrobial agents and published reports demonstrating that plant extracts are widely applied in modern medicine, reporting potential activity that may be due to polyphenol compounds. Interestingly, the effects of polyphenols on the sensitivity of bacteria to antibiotics have not been well-studied. Hence, the current review encompasses the prospective applicat...
Source: Medicinal Chemistry - April 8, 2024 Category: Chemistry Authors: Alok Sharma None Anurag Jasleen Kaur Anuradh Kesharwani Vipan Parihar Source Type: research
A Computational Study of Green Tea Extracts and their Derivatives as Potential Inhibitors for Squalene Monooxygenase
CONCLUSION: The results obtained from this study suggest that green tea polyphenols have the potential for inhibition of squalene monooxygenase, except for theasinensin A.PMID:38584555 | DOI:10.2174/0115734064280290240211170037 (Source: Medicinal Chemistry)
Source: Medicinal Chemistry - April 8, 2024 Category: Chemistry Authors: Kabelo Phuti Mokgopa Kevin A Lobb Tendamudzimu Tshiwawa Source Type: research
Antimicrobial Potential of Polyphenols: An Update on Alternative for Combating Antimicrobial Resistance
Med Chem. 2024 Apr 5. doi: 10.2174/0115734064277579240328142639. Online ahead of print.ABSTRACTThe last decade has encountered an increasing demand for plant-based natural antibiotics. This demand has led to more research-based investigations for natural sources of antimicrobial agents and published reports demonstrating that plant extracts are widely applied in modern medicine, reporting potential activity that may be due to polyphenol compounds. Interestingly, the effects of polyphenols on the sensitivity of bacteria to antibiotics have not been well-studied. Hence, the current review encompasses the prospective applicat...
Source: Medicinal Chemistry - April 8, 2024 Category: Chemistry Authors: Alok Sharma None Anurag Jasleen Kaur Anuradh Kesharwani Vipan Parihar Source Type: research
A Computational Study of Green Tea Extracts and their Derivatives as Potential Inhibitors for Squalene Monooxygenase
CONCLUSION: The results obtained from this study suggest that green tea polyphenols have the potential for inhibition of squalene monooxygenase, except for theasinensin A.PMID:38584555 | DOI:10.2174/0115734064280290240211170037 (Source: Medicinal Chemistry)
Source: Medicinal Chemistry - April 8, 2024 Category: Chemistry Authors: Kabelo Phuti Mokgopa Kevin A Lobb Tendamudzimu Tshiwawa Source Type: research
Antimicrobial Potential of Polyphenols: An Update on Alternative for Combating Antimicrobial Resistance
Med Chem. 2024 Apr 5. doi: 10.2174/0115734064277579240328142639. Online ahead of print.ABSTRACTThe last decade has encountered an increasing demand for plant-based natural antibiotics. This demand has led to more research-based investigations for natural sources of antimicrobial agents and published reports demonstrating that plant extracts are widely applied in modern medicine, reporting potential activity that may be due to polyphenol compounds. Interestingly, the effects of polyphenols on the sensitivity of bacteria to antibiotics have not been well-studied. Hence, the current review encompasses the prospective applicat...
Source: Medicinal Chemistry - April 8, 2024 Category: Chemistry Authors: Alok Sharma None Anurag Jasleen Kaur Anuradh Kesharwani Vipan Parihar Source Type: research
A Computational Study of Green Tea Extracts and their Derivatives as Potential Inhibitors for Squalene Monooxygenase
CONCLUSION: The results obtained from this study suggest that green tea polyphenols have the potential for inhibition of squalene monooxygenase, except for theasinensin A.PMID:38584555 | DOI:10.2174/0115734064280290240211170037 (Source: Medicinal Chemistry)
Source: Medicinal Chemistry - April 8, 2024 Category: Chemistry Authors: Kabelo Phuti Mokgopa Kevin A Lobb Tendamudzimu Tshiwawa Source Type: research
Antimicrobial Potential of Polyphenols: An Update on Alternative for Combating Antimicrobial Resistance
Med Chem. 2024 Apr 5. doi: 10.2174/0115734064277579240328142639. Online ahead of print.ABSTRACTThe last decade has encountered an increasing demand for plant-based natural antibiotics. This demand has led to more research-based investigations for natural sources of antimicrobial agents and published reports demonstrating that plant extracts are widely applied in modern medicine, reporting potential activity that may be due to polyphenol compounds. Interestingly, the effects of polyphenols on the sensitivity of bacteria to antibiotics have not been well-studied. Hence, the current review encompasses the prospective applicat...
Source: Medicinal Chemistry - April 8, 2024 Category: Chemistry Authors: Alok Sharma None Anurag Jasleen Kaur Anuradh Kesharwani Vipan Parihar Source Type: research
A Computational Study of Green Tea Extracts and their Derivatives as Potential Inhibitors for Squalene Monooxygenase
CONCLUSION: The results obtained from this study suggest that green tea polyphenols have the potential for inhibition of squalene monooxygenase, except for theasinensin A.PMID:38584555 | DOI:10.2174/0115734064280290240211170037 (Source: Medicinal Chemistry)
Source: Medicinal Chemistry - April 8, 2024 Category: Chemistry Authors: Kabelo Phuti Mokgopa Kevin A Lobb Tendamudzimu Tshiwawa Source Type: research
Antimicrobial Potential of Polyphenols: An Update on Alternative for Combating Antimicrobial Resistance
Med Chem. 2024 Apr 5. doi: 10.2174/0115734064277579240328142639. Online ahead of print.ABSTRACTThe last decade has encountered an increasing demand for plant-based natural antibiotics. This demand has led to more research-based investigations for natural sources of antimicrobial agents and published reports demonstrating that plant extracts are widely applied in modern medicine, reporting potential activity that may be due to polyphenol compounds. Interestingly, the effects of polyphenols on the sensitivity of bacteria to antibiotics have not been well-studied. Hence, the current review encompasses the prospective applicat...
Source: Medicinal Chemistry - April 8, 2024 Category: Chemistry Authors: Alok Sharma None Anurag Jasleen Kaur Anuradh Kesharwani Vipan Parihar Source Type: research
A Computational Study of Green Tea Extracts and their Derivatives as Potential Inhibitors for Squalene Monooxygenase
CONCLUSION: The results obtained from this study suggest that green tea polyphenols have the potential for inhibition of squalene monooxygenase, except for theasinensin A.PMID:38584555 | DOI:10.2174/0115734064280290240211170037 (Source: Medicinal Chemistry)
Source: Medicinal Chemistry - April 8, 2024 Category: Chemistry Authors: Kabelo Phuti Mokgopa Kevin A Lobb Tendamudzimu Tshiwawa Source Type: research
Antimicrobial Potential of Polyphenols: An Update on Alternative for Combating Antimicrobial Resistance
Med Chem. 2024 Apr 5. doi: 10.2174/0115734064277579240328142639. Online ahead of print.ABSTRACTThe last decade has encountered an increasing demand for plant-based natural antibiotics. This demand has led to more research-based investigations for natural sources of antimicrobial agents and published reports demonstrating that plant extracts are widely applied in modern medicine, reporting potential activity that may be due to polyphenol compounds. Interestingly, the effects of polyphenols on the sensitivity of bacteria to antibiotics have not been well-studied. Hence, the current review encompasses the prospective applicat...
Source: Medicinal Chemistry - April 8, 2024 Category: Chemistry Authors: Alok Sharma None Anurag Jasleen Kaur Anuradh Kesharwani Vipan Parihar Source Type: research
A Computational Study of Green Tea Extracts and their Derivatives as Potential Inhibitors for Squalene Monooxygenase
CONCLUSION: The results obtained from this study suggest that green tea polyphenols have the potential for inhibition of squalene monooxygenase, except for theasinensin A.PMID:38584555 | DOI:10.2174/0115734064280290240211170037 (Source: Medicinal Chemistry)
Source: Medicinal Chemistry - April 8, 2024 Category: Chemistry Authors: Kabelo Phuti Mokgopa Kevin A Lobb Tendamudzimu Tshiwawa Source Type: research
Antimicrobial Potential of Polyphenols: An Update on Alternative for Combating Antimicrobial Resistance
Med Chem. 2024 Apr 5. doi: 10.2174/0115734064277579240328142639. Online ahead of print.ABSTRACTThe last decade has encountered an increasing demand for plant-based natural antibiotics. This demand has led to more research-based investigations for natural sources of antimicrobial agents and published reports demonstrating that plant extracts are widely applied in modern medicine, reporting potential activity that may be due to polyphenol compounds. Interestingly, the effects of polyphenols on the sensitivity of bacteria to antibiotics have not been well-studied. Hence, the current review encompasses the prospective applicat...
Source: Medicinal Chemistry - April 8, 2024 Category: Chemistry Authors: Alok Sharma None Anurag Jasleen Kaur Anuradh Kesharwani Vipan Parihar Source Type: research
A Computational Study of Green Tea Extracts and their Derivatives as Potential Inhibitors for Squalene Monooxygenase
CONCLUSION: The results obtained from this study suggest that green tea polyphenols have the potential for inhibition of squalene monooxygenase, except for theasinensin A.PMID:38584555 | DOI:10.2174/0115734064280290240211170037 (Source: Medicinal Chemistry)
Source: Medicinal Chemistry - April 8, 2024 Category: Chemistry Authors: Kabelo Phuti Mokgopa Kevin A Lobb Tendamudzimu Tshiwawa Source Type: research
Promising Potential of Curcumin and Related Compounds for Antiviral Drug Discovery
Med Chem. 2024 Apr 2. doi: 10.2174/0115734064277371240325105016. Online ahead of print.ABSTRACTViruses are acellular, microscopic, and mobile particles containing genetic particles, either DNA/RNA strands as nucleoproteins, responsible for 69,53,743 deaths till the year 2023. Curcumin and related compounds are among the areas of pivotal interest for researchers because of their versatile pharmacological profile. Chemically known as diferuloylmethane, which is a main constituent of turmeric along with demethoxycurcumin and bisdemethoxycurcumin, they have a broad spectrum of antiviral activity against viruses such as human i...
Source: Medicinal Chemistry - April 4, 2024 Category: Chemistry Authors: Archana Sharma Twinkle Sharma Rajveer Bhaskar Monika Ola Alok Sharma Vijay Kumar Thakur Prabodh Chander Sharma Source Type: research
