Association Between Depression and Antiretroviral Therapy Use Among People Living with HIV: A Meta-analysis

AbstractDepression is common among people living with HIV (PLHIV). Studies on the relationship between depression and use of antiretroviral therapy (ART) are inconclusive. A meta-analysis was conducted to summarize the relationship between depression and ART use among PLHIV. Ten electronic databases, conference abstracts, and dissertations were searched. A random effects meta-analysis was performed to pool the odds ratio estimates from eligible studies. Subgroup analyses and meta-regression were conducted for moderator analysis. Sensitivity analysis was performed to find influential studies. A funnel plot, the Egger test, and the trim and fill analysis were used to detect publication bias. The pooled sample size was 7375 PLHIV from nine eligible studies. The pooled prevalence of depression was 41% (95% confidence interval [CI] 29 –53%). The pooled ART use rate was 52% (95% CI 37–67%). PLHIV with depression were 14% less likely (pooled odds ratio [OR] = 0.86; 95% CI 0.71–1.05) to use ART than those without depression. Subgroup analyses showed that depression was significantly associated with no ART use (pooled OR 0.84 ; 95% CI 0.71–0.99) among studies with a prospective study design (11 estimates from nine studies). Moderator analyses did not show any statistically significant effects. The publication bias analyses showed small study effects may not exist. Depression was associated with non-use of ART among PLH IV. Studies are needed to explor...
Source: AIDS and Behavior - Category: Infectious Diseases Source Type: research

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Source: AIDS Care - Category: Infectious Diseases Authors: Source Type: research
For decades, Tim Lennon repressed memories of the childhood abuse he says he suffered at the hands of a priest. It wasn’t until 1995, when Lennon was in his late 40s and living in San Francisco, that he stumbled across information about clergy sexual abuse and felt decades-old memories come flooding back. “I said, ‘Oh my god, that happened to me,'” Lennon remembers. But even that moment, he says, didn’t prepare him for the memories that resurfaced in 2010 — an avalanche that he believes was triggered by his twin daughters turning 12, the age around which he says he was raped by a priest....
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime Mental Health/Psychology onetime Source Type: news
AIDS Research and Human Retroviruses, Ahead of Print.
Source: AIDS Research and Human Retroviruses - Category: Infectious Diseases Authors: Source Type: research
What is holistic therapy? Holistic therapy is defined as non-medicinal recovery methods. At Cliffside, we use holistic therapy to complement traditional treatment practices. Holistic therapy aims to bring the mind, body and spirit into alignment. It focuses on the patient’s overall well-being while also treating physical symptoms of addiction and withdrawal. They can be very beneficial to addiction therapy because they can be calming, healing outlets to use in place of old behaviors. They support the constant growth of each patient – mentally, physically, emotionally and spiritually. Holistic therapy aids in he...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Acupuncture Addiction Addiction Recovery Alcohol Alcohol Rehab Information Alcoholism Complementary Therapies Drinking Drug Rehab Information Drug Treatment Eating Disorders Exercise Healthy Eating and Recovery Holistic Treatment Source Type: blogs
In this study, we prospectively examined the association of cigarette smoking with food insecurity in a cohort of 108 individuals seeking vocational rehabilitation services. Over the 12-month study period, smokers at baseline reported consistently higher levels of food insecurity compared to non-smokers. Smoking remained an independent risk factor for greater food insecurity, controlling for sociodemographic characteristics and known confounders (e.g., substance use, depression). Food insecurity is a key structural and socioeconomic barrier that may partially explain HIV-related health disparities observed among smokers. F...
Source: AIDS and Behavior - Category: Infectious Diseases Source Type: research
July 30, 2018She knows from experience that health workers can either push LGBTI clients away from the care they need —or draw them to it.When I met Sempijja Dalausi, aka Mrs. Pontoshi, the first thing I noticed was her infectious laugh.  A transgender woman and former sex worker, Mrs. Pontoshi lives with HIV in rural Uganda. And she ’s working toward a world where all members of the lesbian, gay, bisexual, transgender, and intersex (LGBTI) community have access to high-quality HIV services.Stigmatized and marginalizedDenial was her first reaction when she tested positive in October 2009.Despite couns...
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Source Type: news
Conditions:   HIV/AIDS;   STI;   Gender Dysphoria;   Transsexualism;   Gender Identity;   Depression, Anxiety Intervention:   Other: Medical gender affirmation Sponsors:   Fenway Community Health;   Callen-Lorde Community Health Center;   Patient-Centered Outcomes Research Institute Not yet recruiting
Source: - Category: Research Source Type: clinical trials
Abstract The discovery of "oestrus-producing" hormones was a major research breakthrough in biochemistry and pharmacology during the early part of the 20th century. The elucidation of the molecular weight and chemical structure of major oxidative metabolites of dehydroepiandrosterone (DHEA) led to the award of the Nobel Prize in 1939 to Adolf Frederick Johann Butenandt and Leopold Ruzicka. Considered a bulk androgen in the circulation, DHEA and its sulfated metabolite DHEA-S can be taken up by most tissues where the sterols are metabolized to active androgenic and estrogenic compounds needed for growth a...
Source: Vitamins and Hormones - Category: Endocrinology Authors: Tags: Vitam Horm Source Type: research
Volume 30, Issue sup1, January - December 2018, Page 29-36 .
Source: AIDS Care - Category: Infectious Diseases Authors: Source Type: research
Sadly, stigma around health conditions remains a part of many patients ’ lives. Many will not disclose a diagnosis for fear of being judged by peers, employers, health professionals, colleagues and wider society. In fact, there is clear evidence that such negative societal attitudes impact health outcomes, resulting in diagnosis delays and impaired treatment.Some diseases are heavily stigmatized – including mental health, HIV/AIDS, hepatitis and some skin conditions – leading people to restrict their participation in society, impairing their chances of living happy, healthy lives.However, to one extent or...
Source: EyeForPharma - Category: Pharmaceuticals Authors: Source Type: news
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