Improving Patient Adherence to Treatment and Prevention Regimens to Promote Health (R01)

Research grants that address patient adherence to treatment and prevention regimens to promote positive health outcomes. Clinical trials are optional. Geographic coverage: Nationwide -- National Cancer Institute, National Center for Complementary and Integrative Health, National Institute of Allergy and Infectious Diseases, National Institute of Mental Health, National Institute of Nursing Research, National Institute on Aging, National Institute on Alcohol Abuse and Alcoholism, National Institute on Drug Abuse, National Institute on Minority Health and Health Disparities, National Institutes of Health, U.S. Department of Health and Human Services
Source: AIDS and HIV funding opportunities via the Rural Assistance Center - Category: Infectious Diseases Source Type: funding

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Publication date: Available online 3 June 2020Source: Life SciencesAuthor(s): Milad Ashrafizadeh, Ali Zarrabi, Kiavash Hushmandi, Vahideh Zarrin, Ebrahim Rahmani Moghadam, Amirhossein Zabolian, Shima Tavakol, Saeed Samarghandian, Masoud Najafi
Source: Life Sciences - Category: Biology Source Type: research
Publication date: 1 September 2020Source: Life Sciences, Volume 256Author(s): Neda Khalili, Masoud Nouri-Vaskeh, Zahra Hasanpour Segherlou, Amir Baghbanzadeh, Monireh Halimi, Haleh Rezaee, Behzad Baradaran
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 2 June 2020Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Ping Huang, Guanchun Wang, Zhaohong Wang, Cancan Zhang, Fengmian Wang, Xiaoxiao Cui, Sini Guo, Wei Huang, Rong Zhang, Deyue Yan
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
Publication date: 24 September 2020Source: Inorganica Chimica Acta, Volume 510Author(s): Thankaraj Salammal Sheena, Rajakumaran Dhivya, Venkatesan Rajiu, K. Jeganathan, Mallayan Palaniandavar, Ganesan Mathan, Mohammad Abdulkader Akbarsha
Source: Inorganica Chimica Acta - Category: Chemistry Source Type: research
Dalton Trans., 2020, Advance Article DOI: 10.1039/C9DT04927D, PaperMei-Ling Cheng, Meng-Na Qin, Lin Sun, Lu Liu, Qi Liu, Xiao-Yan Tang A Cu(II)-pyrazoledicarboxylate MOF displayed high activity and selectivity in the base-free oxidation of benzyl alcohol to benzaldehyde combined with H2O2. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - Category: Chemistry Authors: Source Type: research
CONCLUSIONS: The introduction of spacer sequence between chelator and BBN(7-14) led to improved bidistribution. Analogue with tri-Gly spacer is the more promising radiopeptide for targeting GRP receptor than Ser conjugate. Therefore, these analogs can be considered as a candidate for the identification of bombesin-positive tumors. PMID: 32497000 [PubMed - as supplied by publisher]
Source: Current Radiopharmaceuticals - Category: Radiology Tags: Curr Radiopharm Source Type: research
Authors: Ao H, Li Y, Li H, Wang Y, Han M, Guo Y, Shi R, Yue F, Wang X Abstract Hydroxy genkwanin (HGK), a flavonoid compound from natural resources, showed good inhibition against the growth of breast tumor cells. However, the poor solubility restricted the further study and the in vivo drug delivery of HGK. We prepared HGK nanosuspensions by antisolvent precipitation method and investigated their characterization, stability, hemolysis probability, release behavior in vitro, antitumor activity in vitro and in vivo, and preliminary safety through acute toxicity experiments. The resultant HGK nano...
Source: Drug Delivery - Category: Drugs & Pharmacology Tags: Drug Deliv Source Type: research
Authors: Zhang X, Ren X, Tang J, Wang J, Zhang X, He P, Yao C, Bian W, Sun L Abstract Multidrug resistance (MDR) of cancer cells is a significant challenge in chemotherapy, highlighting the urgent medical need for simple and reproducible strategies to reverse this process. Here, we report the development of an active tumor-targeting and redox-responsive nanoplatform (PA-ss-NP) using hyaluronic acid-g-cystamine dihydrochloride-poly-ε-(benzyloxycarbonyl)-L-lysine (HA-ss-PLLZ) to co-deliver paclitaxel (PTX) and apatinib (APA) for effective reversal of MDR. This smart nanoplatform specifically bound to CD44 rec...
Source: Drug Delivery - Category: Drugs & Pharmacology Tags: Drug Deliv Source Type: research
Authors: Mookerjee S, Foster HR, Waller AK, Ghevaert CJ Abstract Platelet transfusions are given to patients in hospital who have a low blood platelet count (thrombocytopenia) either because of major bleeding (following trauma or surgery) or because the bone marrow production of platelets is impaired often due to chemotherapy, infiltration with malignant cells, fibrosis or genetic disorders. We are currently entirely reliant on blood donors as a source of platelets in transfusion medicine. However, the demand for platelets continues to rise, driven by an aging population, advances in medical procedures and ever mor...
Source: Platelets - Category: Hematology Tags: Platelets Source Type: research
Joanna Mikulak1,2, Elena Bruni1,2, Ferdinando Oriolo1,2, Clara Di Vito1 and Domenico Mavilio1,2* 1Unit of Clinical and Experimental Immunology, Humanitas Clinical and Research Center, Milan, Italy 2Department of Medical Biotechnologies and Translational Medicine, University of Milan, Milan, Italy The liver is considered a preferential tissue for NK cells residency. In humans, almost 50% of all intrahepatic lymphocytes are NK cells that are strongly imprinted in a liver-specific manner and show a broad spectrum of cellular heterogeneity. Hepatic NK (he-NK) cells play key roles in tuning liver immune response in b...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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