Fertility Clinic Meltdowns Destroyed Frozen Eggs and Embryos. What Happens Now?

Simultaneous refrigeration failures at two fertility clinics in San Francisco and suburban Cleveland have damaged or destroyed potentially thousands of frozen eggs and embryos in the biggest such loss on record in the U.S. The malfunctions have left parents-to-be heartbroken and baffled experts. Here are some questions and answers about the two cases. ___ What happened? In Ohio, University Hospitals Cleveland Medical Center estimates 2,000 eggs and embryos may have been damaged or destroyed when an unexplained storage tank malfunction caused temperatures to rise on March 4. The medical center apologized. On the same day in San Francisco, an embryologist at the Pacific Fertility Clinic noticed the liquid nitrogen level in one tank was very low during a routine check, clinic president Dr. Carl Herbert told ABC. He said the tank was immediately replenished and the embryos were later transferred to a new tank. There’s no known connection between the two episodes, said Dr. Kevin Doody, lab director at the Center for Assisted Reproduction in Texas and past president of the Society for Assisted Reproductive Technology. He said such breakdowns are extremely rare, and two at once is “beyond stunning.” “It’s two black swan events happening in the same day. One of them causes the beehive to buzz. Two? We’re all in shock,” Doody said. Officials have yet to say exactly what went wrong. Barbara Collura, president of the patient advocacy group RESO...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized APH fertility healthytime onetime Source Type: news

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CHELMSFORD (CBS) – Infertility can be a painful experience for couples trying to start a family. It’s a roller coaster ride of emotion that Shawn and Shannon McNamee know well. For more than a year, Shannon injected herself hundreds of times. They tried several rounds of in vitro fertilization (IVF). Nothing worked. “You would get really hopeful and optimistic, then it would crash. The results came back negative every time,” Shawn told WBZ-TV. The McNamees decided to adopt and now their living room is filled with toys and their hearts with love. Their son Logan is happy and curious and in no way int...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Healthwatch Syndicated Local Dr. Mallika Marshall Embryo Adoption Source Type: news
Abstract Context: Maternal metabolic status reflects underlying physiological changes in the maternal-placental-fetal unit, which can identify contributors to adverse pregnancy outcomes associated with infertility and treatments utilized. Objective: To determine if maternal metabolomic profiles are different between spontaneous pregnancies and pregnancies conceived with fertility treatments, including in vitro fertilization (IVF) and non-IVF fertility treatments (NIFT) that may explain differences in pregnancy outcomes. Design: Metabolon® metabolomic analysis and ELISA assays for 17-β-estradiol ...
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
Authors: Macut D, Milutinović DV, Rašić-Marković A, Nestorov J, Bjekić-Macut J, Stanojlović O Abstract Over the last decade, huge achievements have been made in the fields of neurophysiology, molecular endocrinology, and biochemistry, as well as in the successful translation of clinical research into diseases into clinical practice. As regards female reproduction, most of the advances made in this area were achieved in gonadal axis regulation, regulation of behavior through sex steroids, reproductive genetics, preservation of ovarian reproductive function, steroid profiling, and metabolic and overall re...
Source: Hormones - Category: Endocrinology Tags: Hormones (Athens) Source Type: research
Conditions:   Infertility;   Progesterone;   Frozen Embryo Transfer;   Euploid Embryo Transfer;   Pregnancy Outcome;   Artificial Cycle;   Ongoing Pregnancy Interventions:   Drug: Low Progesterone;   Drug: Normal Progesterone Sponsors:   Institut Universitari Dexeus;   Fundación Santiago Dexeus Font;   Dexeus Mujer Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionThis program was evaluated positively. The AALS, PTGI ‐J, EPDS, and STAI showed significant change after the program and the AALS, PTGI‐J, and STAI‐J showed significant correlations with the CNSS.
Source: Japan Journal of Nursing Science - Category: Nursing Authors: Tags: ORIGINAL ARTICLE Source Type: research
I am still not able to cope up with negative pregnancy test. I just wished that the test still comes positive. My good looking embryos do not like to settle in my good looking endometrium lining. I wish that I could know what these beautiful embryos wants more from me? Why all these medicines,efforts, patience, care, precautions and prayers for having a baby is not paying off. What else can we do to fulfill our dream to have a baby ?Crying is also not helping. After getting result, I spent entire day in reading positive ivf stories on internet I know that in this journey nobody get success immediately, every couple have th...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
ConclusionThere is limited evidence on the ectopic pregnancy prevalence in Iranian obstetrical clients and assisted reproductive technologies patients. Furthermore, a significant heterogeneity existed between the results. So, more population ‐based studies on national data are needed for the exact estimation of the ectopic pregnancy prevalence in Iran.
Source: Journal of Evidence-Based Medicine - Category: General Medicine Authors: Tags: ARTICLE Source Type: research
Conclusions: The delayed start protocol was not associated with better conception results or cycle outcomes in poor responders with primary infertility undergoing IVF cycles. PMID: 30410693 [PubMed]
Source: Oman Medical Journal - Category: Middle East Health Tags: Oman Med J Source Type: research
CONCLUSION: Elective oocyte cryopreservation is a feasible option for successful pregnancy in patients opposed to embryo cryopreservation. PMID: 30408388 [PubMed]
Source: Journal of Reproductive Medicine - Category: Reproduction Medicine Tags: J Reprod Med Source Type: research
Authors: Hudecek R, Huser M, Pdnkovi S, Mekiniovi L, Kadlecovi J, Ventruba P Abstract OBJECTIVE: To determine the efficacy and safety of intramyometrial application of epinephrine during a laparoscopic myomectomy in women of reproductive age desiring pregnancy and with clinically symptomatic uter- ine fibroids, in comparison with a placebo-based patient control group. STUDY DESIGN: The study group (n=96, 53.3%) underwent an application of 12 μg epinephrine hydro- chloride diluted in 20 mL of NaCl solution, while the control group (n=84, 46.7%) received 20 mL of NaCl only. Perioperative blood loss, duration o...
Source: Journal of Reproductive Medicine - Category: Reproduction Medicine Tags: J Reprod Med Source Type: research
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