Fertility Clinic Meltdowns Destroyed Frozen Eggs and Embryos. What Happens Now?
Simultaneous refrigeration failures at two fertility clinics in San Francisco and suburban Cleveland have damaged or destroyed potentially thousands of frozen eggs and embryos in the biggest such loss on record in the U.S. The malfunctions have left parents-to-be heartbroken and baffled experts. Here are some questions and answers about the two cases. ___ What happened? In Ohio, University Hospitals Cleveland Medical Center estimates 2,000 eggs and embryos may have been damaged or destroyed when an unexplained storage tank malfunction caused temperatures to rise on March 4. The medical center apologized. On the same day in San Francisco, an embryologist at the Pacific Fertility Clinic noticed the liquid nitrogen level in one tank was very low during a routine check, clinic president Dr. Carl Herbert told ABC. He said the tank was immediately replenished and the embryos were later transferred to a new tank. There’s no known connection between the two episodes, said Dr. Kevin Doody, lab director at the Center for Assisted Reproduction in Texas and past president of the Society for Assisted Reproductive Technology. He said such breakdowns are extremely rare, and two at once is “beyond stunning.” “It’s two black swan events happening in the same day. One of them causes the beehive to buzz. Two? We’re all in shock,” Doody said. Officials have yet to say exactly what went wrong. Barbara Collura, president of the patient advocacy group RESO...
[Nairobi News] Two in every 10 couples suffer from infertility, data has shown.
CONCLUSION: Trends favoring twice daily dosing are encouraging findings and require further investigation. PMID: 29999292 [PubMed - in process]
CONCLUSION: Expression of gap junction protein correlates with quantity of oocytes retrieved and might be related to pregnancy outcome. This study suggests that lack of connexin43 expression may contribute to poor ovarian response. PMID: 29999282 [PubMed - in process]
Uterine myomas are common benign monoclonal tumors with extremely low potential for malignancy. They are estimated to be present in up to 70% of women of reproductive age , with a higher incidence in obese women and those of African American descent, and when symptomatic, a frequent indication for gynecologic surgery. Although the presence of myomas may be associated with a plethora of symptoms including pelvic pain, abnormal uterine bleeding, infertility/subfertility, and adverse pregnancy outcomes , the vast majority of women with uterine fibroids are asymptomatic.
BY GREGORY TAYLOR, DO, &JACKLYN MCPARLANE, DOA 31-year-old woman with a significant medical history for one ectopic pregnancy and five spontaneous abortions presented with abdominal pain and vaginal bleeding. Her symptoms started abruptly two days earlier, and the pain was located in the right lower quadrant, which had become diffuse and she described as sharp. She was also experiencing nausea, vomiting, and vaginal bleeding.She stated she had been spotting for five days and soaking up to four pads a day. Her last menstrual period was two months before, and a home pregnancy test was positive. Her presentation was...
We report a case of OEIS complex with the classical four major components in a 2-hour old term male baby, delivered by cesarean section to a 37-year-old lady with history of primary infertility and had the pregnancy with the aid of In Vito Fertilization. The baby was one of a set of twins. The other baby was alive and normal. We document the presence of a vesico-enteric fistula between the urinary bladder and the terminal ileum, which is to our best knowledge, a unique association that is not reported in the reviewed studies. We present the immediate neonatal care and surgical intervention that has been done for this newborn.
In conclusion, with strict repeated assessments of blood parameters and maintenance of the platelet count, the bleeding risk in pregnancy in DIAPH1-related disease can be successfully controlled. PMID: 29985732 [PubMed - as supplied by publisher]
Publication date: July 2018Source: Reproductive BioMedicine Online, Volume 37, Issue 1Author(s): Xianghui Zhang, Dong Liu, Wei Huang, Qiushi Wang, Xue Feng, Jing TanAbstractThe effect of endometriosis on fecundity is unclear. Although surgery plays a vital role in the treatment of related infertility, pregnancy outcomes after laparoscopy are poorly correlated with the currently used staging system. To address this, the Endometriosis Fertility Index (EFI) was developed. This retrospective study was designed to assess the predictive value of the EFI for patients with endometriosis-associated infertility. A total of 1325 pati...
ConclusionsThe processes related to the differentially expressed proteins play important roles in fecundity and fecundability. The present study may reveal the cause of various endometrial aberrations as a limiting factor for achieving pregnancy in PCOS women.
Conclusion(s)Pregnancy/retrieval and ongoing pregnancy rates are comparable among the three protocols with GnRH agonist stop protocol having non-significantly higher rates.