Prevalent Digoxin Use and Subsequent Risk of Death or Hospitalization in Ambulatory Heart Failure Patients with a Reduced Ejection Fraction – Findings from the HF-ACTION Randomized Controlled Trial

Conclusion Although digoxin use was associated with high-risk clinical features, the association between digoxin therapy and outcomes was dependent on the statistical methods used for multivariable adjustment. Clinical equipoise exists and additional prospective research is required to clarify the role of digoxin in contemporary clinical practice including its effects on functional capacity, quality of life, and long-term outcomes.
Source: American Heart Journal - Category: Cardiology Source Type: research