Central nervous system involvement in rheumatoid arthritis: possible role of chronic inflammation and tnf blocker therapy

In conclusion, next to decreasing disease activity and joint erosions by suppressing in flammation, anti-TNF therapy in RA can also suppress potential CNS involvement linked to BBB (blood–brain barrier) dysfunction. Further studies with broader participation and longer patient follow-up are needed to reinforce this hypothesis.
Source: Acta Neurologica Belgica - Category: Neurology Source Type: research