Anesthesia for Lung Transplantation in Cystic Fibrosis: Retrospective Review from the Irish National Transplantation Centre
Cystic fibrosis (CF) is an autosomal recessive disorder affecting approximately 1 in 2,500 live births worldwide, with double this estimated frequency in Ireland. CF is characterized by a genetic defect of the CF transmembrane regulator protein, causing impairment of chloride ion transportation. This has multisystem consequences, particularly in the lungs, where it results in intensely mucoid secretions, which increases susceptibility to infection. Lung transplantation is indicated in CF when there is progressive decline in a patient ’s functional reserve.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Martin Lenihan, Darren Mullane, Donal Buggy, Georgina Flood, Michael Griffin Tags: Special Article Source Type: research
More News: Anesthesia | Anesthesiology | Cardiology | Chloride | Cystic Fibrosis | Genetics | Heart | Ireland Health | Lung Transplant | Transplants