Focused ultrasound-facilitated brain drug delivery using optimized nanodroplets: vaporization efficiency dictates large molecular delivery.

In conclusion, the vaporization efficiency of nanodroplets positively impacted the amount of molecules delivered to the brain. The OFP droplets due to the higher vaporization efficiency served as better acoustic agents to deliver large molecules safely and efficiently to the brain compared with the DFB droplets.
PMID: 29260735 [PubMed - as supplied by publisher]

Source: Physics in Medicine and Biology - December 20, 2017 Category: Physics Authors: Wu SY, Fix SM, Arena CB, Chen CC, Zheng W, Olumolade OO, Papadopoulou V, Novell A, Dayton PA, Konofagou EE Tags: Phys Med Biol Source Type: research