In silico design of RNA nanoparticles

The National Cancer Institute seeks parties interested in licensing or collaborative research to co-develop RNA nanostructures using computational and synthetic methods.IC: NCINIH Ref. No.: E-059-2009Advantages: RNA nanoparticles potentially offer advantages compared to other conventional nanoparticles:They are compatible with biological systems and thus may be readily used for in vivo applications such as therapeutic and diagnostic.They are small and have a potential to move efficiently through biological barriers to a target tissue.They have multiple binding sites and thus can readily be conjugated with several functional groups (e.g. therapeutic molecule and targeting molecule).They are versatile and can be designed in different shapes and sizes for different applications and can alter their shapes and functionality under different environmental conditions.Applications: Cancer therapeuticsDiagnostic and imaging toolsGene TherapyNanocircuitsMedical ImplantsDevelopment Status: Pre-clinical (in vivo)Updated On: Dec 20, 2017Provider Classifications: Publications: Patent Application: 61/187495Patent Authority: U.S. ProvisionalPatent Number: 9,732,337Licensing Contacts: Lead Inventor: Inventor IC: NCIInventor Lab URL: https://ccr.cancer.gov/Gene-Regulation-and-Chromosome-Biology-Laboratory/bruce-a-shapiroInv Is lead: LPM Phone: [phone]LPM Email: [e-mail] Classification:&n...

Source: NIH OTT Licensing Opportunities - December 21, 2017 Category: Research Authors: ajoyprabhu3 Source Type: research