Immune cell discovery could help to halt cancer spread
The critical importance of highly specialized immune cells, called natural killer cells, in killing melanoma cells that have spread to the lungs has been highlighted by new research. These natural killer cells could be harnessed to hunt down and kill cancers that have spread in the body, scientists report. The team also found natural killer cells were critical to the body's rejection of donor bone marrow transplants and in the runaway immune response during toxic shock syndrome.
CONCLUSIONS: Radiation therapy continues to be an integral component of the palliative armamentarium against painful metastases. Radiation oncologist, in conjunction with referral physicians, can tailor treatment plans to reflect the needs of a given patient. PMID: 30109789 [PubMed - in process]
CONCLUSIONS: A CNB to confirm mammographic or clinical findings of breast lesions is an accurate method to establish a pathological diagnosis of breast lesions. The accuracy is higher for invasive carcinomas than for non-invasive cancers. Excisional biopsies are necessary for lesions with anticipated sampling errors or when the core needle biopsy findings are discordant with clinical or mammographic findings. PMID: 30109786 [PubMed - in process]
Japan's Eisai Co Ltd said on Thursday it would price its cancer drug Lenvima at about $16,000 for a month's supply before discounts, after the U.S. Food and Drug Administration approved its use in patients with a common form of liver cancer.
At 76, Aretha Franklin died of pancreatic cancer, one of the most deadly forms of the disease. An expert explained to Daily Mail Online why, even with the safer form she had, pancreatic cancer kills.
Publication date: Available online 16 August 2018Source: Journal of Molecular Graphics and ModellingAuthor(s): Jakub Kollar, Vladimir FrecerAbstractInhibitors of histone deacetylase superfamily (HDAC), which induce cell cycle arrest, trigger cell death and reduce angiogenesis appear as promising anti-cancer drugs targeting the epigenetic regulation of gene expression. Approved HDAC inhibitors were found effective against haematological and solid malignancies, other HDACIs are currently in clinical trials for the treatment of neurological diseases or immune disorders. Among those, diarylcyclopropane hydroxamic acids (DCHA) ...
The oral therapy lenvatinib joins sorafenib as the only drugs approved for first-line treatment of patients with unresectable hepatocellular carcinoma.FDA Approvals
Cancer researchers and FBI agents have more in common than one might think at first blush. “We’re chasing down cancer clues, you’re chasing down people trying to do us harm, but ultimately, trying to find the truth,” Dr. Brian Druker, director of the OHSU Knight Cancer Institute, told a group of Oregon FBI officials on Wednesday. Druker was at the Oregon FBI headquarters near t he Portland International Airport as part of the agency’s leadership speaker series. Columbia Sportswear CEO…
Phys. Chem. Chem. Phys., 2018, Accepted Manuscript DOI: 10.1039/C8CP04315A, PaperChristian Solis-Calero, Geancarlo Zanatta, Cl áudia Pessoa, Hernandes Faustino Carvalho, Valder Nogueira Freire Urokinase plasminogen activator (uPA) is a biomarker and therapeutic target for several cancer types whose inhibition has been shown to slow tumor growth and metastasis. In this work, crystallographic data... The content of this RSS Feed (c) The Royal Society of Chemistry
Photochem. Photobiol. Sci., 2018, Advance Article DOI: 10.1039/C7PP00411G, PerspectiveAnne E. Cust, Kriti Mishra, Marianne Berwick This paper illustrates the independent and interactive role of genetic and environmental factors in the etiology of melanoma. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
This study demonstrates reduced survival in non-rural workers who reside in metropolitan area and who present with compromised lymph nodes and metastasis.Resumo O objetivo deste artigo é estimar a sobrevida específica dos pacientes com câncer de pênis atendidos em um hospital de referência em oncologia. Analisou-se 100 casos incidentes de pacientes com câncer de pênis que receberam tratamento no hospital, no período de 2000 a 2011, seguimento até 31 de dezembro de 2012. U tilizou-se como fonte de informação o banco de dados do Registro Hospitalar de C&...