Review of recent advances in the management of hypertrophic cardiomyopathy.

Review of recent advances in the management of hypertrophic cardiomyopathy. Eur Rev Med Pharmacol Sci. 2017 Nov;21(22):5207-5210 Authors: Cao Y, Zhang PY Abstract Hypertrophic cardiomyopathy (HCM) is a complex but common monogenic cardiovascular disorder characterized by unexplained non dilated left ventricular (LV) thickening in the absence of another cardiac or systemic disease. The condition is associated with sudden and unexpected death in young individuals including trained athletes. HCM represents a genetic disorder caused by mutations in genes encoding sarcomeric proteins of the cardiac myocyte. This review article discusses the genetics behind HCM, its clinical presentation, and diagnosis and the present-day pharmacological management of HCM. PMID: 29228435 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research