Constipation is not associated with dopamine transporter pathology in early drug ‐naïve patients with Parkinson's disease

ConclusionsConstipation was not associated with DAT pathology but with rapid eye movement sleep behaviour disorder and depression, which are speculated to be pre‐motor symptoms of PD. This confirms the hypothesis that constipation may be a pre‐motor sign of PD due to an impairment of non‐dopaminergic pathways.
Source: European Journal of Neurology - Category: Neurology Authors: Tags: Original Article Source Type: research