A polyphenol-rich cranberry extract reverses insulin resistance and hepatic steatosis independently of body weight loss

Conclusions Taken together, our findings demonstrate that CE, without impacting body weight or adiposity, can fully reverse HFHS diet-induced insulin resistance and hepatic steatosis while triggering A. muciniphila blooming in the gut microbiota, thus underscoring the gut-liver axis as a primary target of cranberry polyphenols.
Source: Molecular Metabolism - Category: Endocrinology Source Type: research