Detection of mutations in symptomatic patients with hypertrophic cardiomyopathy in Taiwan.

CONCLUSIONS: We identified 13 HCM pedigrees, including 5 carrying novel mutations and 1 with a double mutation. The three most commonly mutated genes were MYH7, MYBPC3, and TNNT2. These results, together with genetic counseling, could lead to earlier diagnosis and better management of family members at risk of HCM.
PMID: 25086479 [PubMed - as supplied by publisher]

Source: Journal of Cardiology - July 30, 2014 Category: Cardiology Authors: Chiou KR, Chu CT, Charng MJ Tags: J Cardiol Source Type: research