Genotype phenotype correlation in Asian Indian von Hippel –Lindau (VHL) syndrome patients with pheochromocytoma/paraganglioma

In conclusion, PCC/PGL are rare in patients with largeVHL deletions and if occur are most likely to be solitary. Patients with bilateral PCC or multifocal PCC/PGL are least likely to have largeVHL deletions. Our study also provides additional evidence for existence of the phenomenon of anticipation in VHL syndrome.
Source: Familial Cancer - Category: Cancer & Oncology Source Type: research