Aldosterone Target NGAL (Neutrophil Gelatinase-Associated Lipocalin) Is Involved in Cardiac Remodeling After Myocardial Infarction Through NF{kappa}B PathwayNovelty and Significance [Heart]

In conclusion, NGAL, a downstream MR activation target, is a key mediator of post-MI cardiac damage. NGAL may be a potential therapeutic target in cardiovascular pathological situations in which MR is involved.

Source: Hypertension - November 8, 2017 Category: Cardiology Authors: Ernesto Martinez–Martinez, Mathieu Buonafine, Ines Boukhalfa, Jaime Ibarrola, Amaya Fernandez–Celis, Peter Kolkhof, Patrick Rossignol, Nicolas Girerd, Paul Mulder, Natalia Lopez–Andres, Antoine Ouvrard–Pascaud, Frederic Jaisser Tags: Basic Science Research Original Articles Source Type: research