The Myokine Irisin Is Released in Response to Saturated Fatty Acids and Promotes Pancreatic {beta}-Cell Survival and Insulin Secretion

In conclusion, irisin can promote β-cell survival and enhance GSIS and may thus participate in the communication between skeletal muscle and β-cells under conditions of excess saturated fatty acids.

Source: Diabetes - October 23, 2017 Category: Endocrinology Authors: Natalicchio, A.; Marrano, N.; Biondi, G.; Spagnuolo, R.; Labarbuta, R.; Porreca, I.; Cignarelli, A.; Bugliani, M.; Marchetti, P.; Perrini, S.; Laviola, L.; Giorgino, F. Tags: Integrated Physiology-Other Hormones Islet Studies Source Type: research