Application of iTRAQ-Based Quantitative Proteomics Approach to Identify Deregulated Proteins Associated with Liver Toxicity Induced by Polygonum Multiflorum in Rats

Conclusion: This iTRAQ proteomics study revealed that the hepatotoxicity induced by PM is primarily related to the oxidative phosphorylation pathways. NADH dehydrogenase family proteins andSlc16a2 could be potential biomarkers of hepatotoxicity resulting from PM.Cell Physiol Biochem 2017;43:2102 –2116
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research