The Role of PPAR alpha in Perfluorooctanoic Acid Induced Developmental Cardiotoxicity and L-carnitine Mediated Protection –Results of in ovo Gene Silencing

In conclusion, PFOA-induced heart rate elevation is likely PPAR alpha independent, while the right ventricular wall thinning seems to be PPAR alpha dependent. The protective effects of L-carnitine do not require PPAR alpha.
Source: Environmental Toxicology and Pharmacology - Category: Environmental Health Source Type: research