Endometriosis and the gift of motherhood

When my first period came at age 13, it involved blood clots and extreme pain. I didn’t know what to expect or what was considered “normal,” but thankfully, my mother did. She recognized that my symptoms were unusual and immediately took me to see my pediatrician. I was first prescribed birth control pills, which seemed to help initially, but when my period remained heavy and painful, I was put on a different birth control pill that enabled me to have my period only four times a year. I thought my situation was normal – albeit uncomfortable and inconvenient. No one ever suggested that painful periods could be anything more than bad luck. I would hear women talk about menstrual cramping and see advertisements for medications to relieve menstrual symptoms … I just figured I had bad periods like so many other adolescent and adult women. I believed that for years. Finding answers to years of pain Then, when I was 22, my cousin Emily was diagnosed with endometriosis. I had never heard of it. I figured it was something extreme because Emily’s symptoms were much more severe than mine. Emily’s mother, my aunt Mary Alice, knew enough about my symptoms that she thought I might have endometriosis as well, even though my symptoms were different than Emily’s. Endometriosis is a chronic condition affecting an estimated 5.5 million women in North America — 30-40% of whom become infertile. It occurs when tissue similar to that which...
Source: Thrive, Children's Hospital Boston - Category: Pediatrics Authors: Tags: Our Patients’ Stories Teen Health endometriosis Marc Laufer Source Type: news

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Source: BMJ Comments - Category: General Medicine Source Type: forums
While becoming pregnant is generally possible for younger breast cancer patients, researchers believe many women change their minds after treatment.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
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Source: Regional Anesthesia and Pain Medicine - Category: Anesthesiology Tags: SPECIAL ARTICLE Source Type: research
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Source: Regional Anesthesia and Pain Medicine - Category: Anesthesiology Tags: EDITORIAL Source Type: research
β-Adrenergic blockade is an important mechanism for reducing morbidity and mortality in patients with hypertension and heart failure. Esmolol has been used widely for its chronotropic and antihypertensive effects. However, there has been recent inquiry regarding perioperative esmolol use and nociceptive modulation. Conventional postoperative analgesic treatment has relied primarily on opioids, which present their own adverse effects and pharmacoepidemiologic repercussions. Esmolol, to date, has not shown any direct analgesic or anesthetic properties; however, recent studies suggest that esmolol may have antinociceptiv...
Source: Regional Anesthesia and Pain Medicine - Category: Anesthesiology Tags: REGIONAL ANESTHESIA AND ACUTE PAIN: DARING DISCOURSE Source Type: research
Conclusions By using patient-specific, 3-dimensionally printed, thoracic spine models, we demonstrated a significant improvement in clinical proficiency as compared with traditional teaching models.
Source: Regional Anesthesia and Pain Medicine - Category: Anesthesiology Tags: REGIONAL ANESTHESIA AND ACUTE PAIN: ORIGINAL ARTICLES Source Type: research
In this study, we hypothesized that the CC approach will produce faster onset of sensory blockade of the 4 major terminal nerves of the brachial plexus than the LS approach. Methods Forty patients undergoing elective upper extremity surgery under a BPB were randomized to receive either the LS (Gp-LS, n = 20) or CC approach (Gp-CC, n = 20) for infraclavicular BPB. Twenty-five milliliters of 0.5% ropivacaine was used for the BPB in both study groups. Sensory-motor blockade of the ipsilateral median, radial, ulnar, and musculocutaneous nerves was assessed by a blinded observer at regular intervals for 45 minutes after the ...
Source: Regional Anesthesia and Pain Medicine - Category: Anesthesiology Tags: REGIONAL ANESTHESIA AND ACUTE PAIN: ORIGINAL ARTICLES Source Type: research
Background and Objectives For superficial surgery of anteromedial and posteromedial surfaces of the upper arm, the medial brachial cutaneous nerve (MBCN) and the intercostobrachial nerve (ICBN) must be selectively blocked, in addition to an axillary brachial plexus block. We compared efficacy of ultrasound-guided (USG) versus conventional block of the MBCN and the ICBN. Methods Eighty-four patients, undergoing upper limb surgery, were randomized to receive either USG (n = 42) or conventional (n = 42) block of the MBCN and the ICBN with 1% mepivacaine. Sensory block was evaluated using light-touch on the upper and lowe...
Source: Regional Anesthesia and Pain Medicine - Category: Anesthesiology Tags: REGIONAL ANESTHESIA AND ACUTE PAIN: ORIGINAL ARTICLES Source Type: research
Background and Objectives Although intravenous lipid emulsion has been proved a powerful antidote for local anesthetic toxicity, there are few pharmacokinetic data on using lipid infusion as a pretreatment for other clinical applications. We assessed the influence of lipid pretreatment on the pharmacodynamics and pharmacokinetics of levobupivacaine. Methods Altogether, 12 patients undergoing below-knee surgery for a fracture were randomly assigned to 2 groups (6 patients per group): pretreatment with 1.5 mL/kg lipid infusion (lipid group) or saline infusion (control subjects) followed by complete femoral and sciatic n...
Source: Regional Anesthesia and Pain Medicine - Category: Anesthesiology Tags: REGIONAL ANESTHESIA AND ACUTE PAIN: ORIGINAL ARTICLES Source Type: research
Conclusions The MPN branches that innervate the lower part of the pectoralis major muscle are asymmetrical and variable in location and length; all located in a triangular area easily defined by sonographic landmarks, lateral to the TAA.
Source: Regional Anesthesia and Pain Medicine - Category: Anesthesiology Tags: REGIONAL ANESTHESIA AND ACUTE PAIN: ORIGINAL ARTICLES Source Type: research
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