MicroRNA-410 regulated lipoprotein lipase variant rs13702 is associated with stroke incidence and modulated by diet in the randomized controlled PREDIMED trial.

Conclusion: We report a novel association between a microRNA target site variant and stroke incidence, which is modulated by diet in terms of decreasing triglycerides and possibly stroke risk in rs13702 C allele carriers after a high-unsaturated fat MedDiet intervention. This trial was registered at controlled-trials.com as ISRCTN35739639.
PMID: 24990426 [PubMed - as supplied by publisher]

Source: The American Journal of Clinical Nutrition - July 2, 2014 Category: Nutrition Authors: Corella D, Sorlí JV, Estruch R, Coltell O, Ortega-Azorín C, Portolés O, Martínez-González MA, Bulló M, Fitó M, Arós F, Lapetra J, Asensio EM, Sáez GT, Serra-Majem L, Muñoz-Bravo C, Ruiz-Gutiérrez V, Fiol M, Vinyoles E, Pintó X, Richardson K, R Tags: Am J Clin Nutr Source Type: research