Integrative studies implicate matrix metalloproteinase ‐12 as a culprit gene for large‐artery atherosclerotic stroke

ConclusionsOur study supports the notion that MMP12 is implicated in large‐artery atherosclerotic stroke, functionally by enhancing elastin degradation and macrophage invasion in plaques.

Source: Journal of Internal Medicine - August 28, 2017 Category: Internal Medicine Authors: H. Mahdessian, L. Perisic Matic, M. Lengquist, K. Gertow, B. Sennblad, D. Baldassarre, F. Veglia, S. E. Humphries, R. Rauramaa, U. Faire, A. J. Smit, P. Giral, S. Kurl, E. Mannarino, E. Tremoli, A. Hamsten, P. Eriksson, U. Hedin, A. M älarstig, Tags: Original Article Source Type: research