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New sperm creation method could overcome genetic male infertility – study

Healthy sperm have been created in mice with a common form of infertility, raising hope for future treatment for men with extra sex chromosomesA common genetic cause of male infertility has been overcome in mice using a technique that creates healthy sperm in the laboratory, scientists have shown.The research raises the future prospect of hope for men who cannot father children because they have three instead of two sex chromosomes.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Fertility problems Reproduction Biology Health Science Society Source Type: news

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Conditions:   Infertility Due to Nonimplantation;   Infertility Intervention:   Drug: Prometrium Sponsor:   Mount Sinai Hospital, Canada Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Embryonic Mosaicism;   Embryo Culture Media;   Embryo Morphokinetics;   Infertility Interventions:   Device: EmbryoScope Plus;   Other: GLOBAL MEDIA;   Other: SAGE MEDIA Sponsor:   University of California, San Francisco Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
What reproductive benefits might high-dose vitamin D supplementation offer infertile men?Journal of Clinical Endocrinology &Metabolism
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
AbstractEssential learning tools for continuing medical education are a challenge in today ’s rapidly evolving field of reproductive medicine. The Midwest Reproductive Symposium International (MRSi) is a yearly conference held in Chicago, IL. The conference is targeted toward physicians, geneticists, nurses, allied health professionals, mental health professionals, business administrati on professionals, and reproductive endocrinology and infertility (REI) fellows engaged in the practice of reproductive medicine. In addition to the scientific conference agenda, there are specific sessions for nurses, mental health pr...
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
Condition:   Infertility Interventions:   Drug: prednisolone;   Drug: Acetyl Salicylic acid Sponsor:   Kasr El Aini Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Infertility, Female Intervention:   Sponsor:   Reproductive & Genetic Hospital of CITIC-Xiangya Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
We report the case of a 46-year-old Chinese male patient who visited our clinic complaining of infertility. Semen analysis revealed azoospermia, and azoospermia factor c region partial deletion (b1/b3) was detected using Y chromosome microdeletion analysis. Testicular sperm extraction was performed after genetic counseling. The bilateral ductus deferens and a portion of the epididymis were absent, whereas the remaining epididymis was expanded. Motile intratesticular spermatozoa were successfully extracted from the seminiferous tubule. On histopathology, nearly complete spermatogenesis was confirmed in almost every seminife...
Source: Clinical and Experimental Reproductive Medicine - Category: Reproduction Medicine Tags: Clin Exp Reprod Med Source Type: research
Conclusion: A considerable knowledge gap about the factors that influence fertility was identified in reproductive-age individuals in an urban area of Thailand. This issue should be urgently addressed by promoting fertility awareness through education, discussions about social perceptions regarding fertility, and reliable sources of knowledge. PMID: 29662824 [PubMed]
Source: Clinical and Experimental Reproductive Medicine - Category: Reproduction Medicine Tags: Clin Exp Reprod Med Source Type: research
Authors: Koo HS, Song IO, Cha SH, Park CW, Kim HO Abstract Objective: To evaluate the pregnancy rate and time to pregnancy after timed coitus with or without superovulation in infertile young women younger than 35 years old with low serum anti-Müllerian hormone (AMH) levels (
Source: Clinical and Experimental Reproductive Medicine - Category: Reproduction Medicine Tags: Clin Exp Reprod Med Source Type: research
Conclusion: These results will be used as basic data for understanding the mechanism of how trophoblast cells respond to oxidative stress and how selenium promotes the upregulation of related genes and improves the survival rate and invasive ability of trophoblasts through regulating mitochondrial activity. These results suggest that selenium may be used in reproductive medicine for purposes including infertility treatment. PMID: 29662820 [PubMed]
Source: Clinical and Experimental Reproductive Medicine - Category: Reproduction Medicine Tags: Clin Exp Reprod Med Source Type: research
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