Left ventricular diastolic dysfunction in women with non-obstructive ischemic heart disease: Insights from magnetic resonance imaging and spectroscopy.

Left ventricular diastolic dysfunction in women with non-obstructive ischemic heart disease: Insights from magnetic resonance imaging and spectroscopy. Am J Physiol Regul Integr Comp Physiol. 2017 Aug 09;:ajpregu.00249.2017 Authors: Nelson MD Abstract Ischemic Heart Disease, in the absence of obstructive coronary artery disease, is prevalent in women, and constitutes a major risk factor for developing major adverse cardiovascular events, including myocardial infarction, stroke, and heart failure. For decades, diagnosis was considered benign and often minimized; however, it is now known that this etiology caries much risk and is a significant burden to the health care system. This review summarizes the current state-of-knowledge on non-obstructive ischemic heart disease (NOIHD), the association between NOIHD and left ventricular diastolic dysfunction, potential links between NOIHD and the development of heart failure with preserved ejection fraction (HFpEF), and therapeutic options and knowledge gaps for patients living with NOIHD. PMID: 28794105 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - Category: Physiology Authors: Tags: Am J Physiol Regul Integr Comp Physiol Source Type: research