Establishment of a murine pancreatic cancer pain model and microarray analysis of pain ‑associated genes in the spinal cord dorsal horn.

In conclusion, the present study has developed a novel animal model of pancreatic cancer pain in BALB/c‑nu mice that resembles human pancreatic cancer pain, and the expression of pain‑associated genes in the spinal cord dorsal horn has been profiled. The results of the present study may further the understanding of the molecular mechanisms that mediate pancreatic cancer pain. PMID: 28791352 [PubMed - as supplied by publisher]
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research