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Establishment of a murine pancreatic cancer pain model and microarray analysis of pain ‑associated genes in the spinal cord dorsal horn.

In conclusion, the present study has developed a novel animal model of pancreatic cancer pain in BALB/c‑nu mice that resembles human pancreatic cancer pain, and the expression of pain‑associated genes in the spinal cord dorsal horn has been profiled. The results of the present study may further the understanding of the molecular mechanisms that mediate pancreatic cancer pain. PMID: 28791352 [PubMed - as supplied by publisher]
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research

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Objectives: The early-stage pancreatic cancer (e-PC; stage I/II) detection rate is quite low at approximately 25%. The aim of this study was to evaluate the feasibility of a social program (the Kishiwada Katsuragi project) wherein our hospital, which specializes in PC, and primary care medical offices (PMOs) used clinical findings to detect e-PC.Methods: Patients with a score of ≥2 points on clinical findings were enrolled: symptoms of abdominal pain/back pain (1 point), new-onset diabetes (1 point), high amylase (AMY) and/or pancreaitc AMY (P-AMY) (1 point), high carbohydrate antigen 19-9 (1 point), and ultrasonography...
Source: Oncology - Category: Cancer & Oncology Source Type: research
Abstract OBJECTIVES: The early-stage pancreatic cancer (e-PC; stage I/II) detection rate is quite low at approximately 25%. The aim of this study was to evaluate the feasibility of a social program (the Kishiwada Katsuragi project) wherein our hospital, which specializes in PC, and primary care medical offices (PMOs) used clinical findings to detect e-PC. METHODS: Patients with a score of ≥2 points on clinical findings were enrolled: symptoms of abdominal pain/back pain (1 point), new-onset diabetes (1 point), high amylase (AMY) and/or pancreaitc AMY (P-AMY) (1 point), high carbohydrate antigen 19-9 (1 poi...
Source: Oncology - Category: Cancer & Oncology Authors: Tags: Oncology Source Type: research
Ladies and Gentlemen, this is the moment you have all been waiting for – the day that the winners of the Medgadget Medical Sci-Fi Competition are announced and their fantastic stories are published! First, we would like to thank Eko Devices, th...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Source Type: blogs
Gene-edited human embryo. Self-driving trucks. Practical quantum computers. 2017 has been an exciting year for science, technology – and digital health! It’s that time of the year again when it’s worth looking back at the past months; and list the inventions, methods and milestone events in healthcare to get a clearer picture what will shape medicine for the years to come. 2017 – Amazing year for science and healthcare Scientists, researchers, and innovators come up with amazing breakthroughs every year, and that was no different in 2017 either. No matter whether we look at physics (proving the exis...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine 3d printing artificial intelligence digital health genetics genomics Healthcare Innovation Personalized medicine robotics technology wearables Source Type: blogs
ConclusionLaparoscopic extended cholecystectomy is technically feasible in patients with T3 GBC, and the extent of resection is the same as that of open surgery.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
In conclusion, rAd-p53 perfusion via the pancreatic artery is a safe and minimally invasive option for the treatment of mid-late stage pancreatic cancer. PMID: 29181104 [PubMed]
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
It was in January 2015 that mother and school teacher Natalie Dunne began having back pain after eating or drinking milk products. Little did she know that the cause was pancreatic cancer.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
BACK PAIN around the middle of your back could be a symptom of pancreatic cancer, along with abdominal pain and indigestion.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
In this study, researchers put some numbers to the correlation, and improve on previous attempts to rule out wealth and other effects as significant contributing causes. A study finds that a Chinese policy is unintentionally causing people in northern China to live 3.1 years less than people in the south, due to air pollution concentrations that are 46 percent higher. These findings imply that every additional 10 micrograms per cubic meter of particulate matter pollution reduces life expectancy by 0.6 years. The elevated mortality is entirely due to an increase in cardiorespiratory deaths, indicating that air poll...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
[Image from unsplash.com]From Novarad touting its VR-surgical guidance system to Zynex paying off its $2.2M loan, here are seven medtech stories we missed this week but thought were still worth mentioning. 1. Stimwave announces first patient in Brazil Stimwave announced in a July 5 press release that its first patients in Brazil have received Stimwave’s wireless pain relief device treatment for chronic pain. The patients are expected to receive the neuromodulation treatment as an alternative to opioid pain relief. The devices created by Stimwave deliver small pulses of energy to specific nerves to trigger a reac...
Source: Mass Device - Category: Medical Devices Authors: Tags: Clinical Trials Diabetes Diagnostics Imaging Neuromodulation/Neurostimulation Pain Management Research & Development American Red Cross Nemaura Medical Novarad Owlstone Medical Stimwave Tactical Medical Zynex Inc. Source Type: news
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