Influence of genetic variants on toxicity to anti-tubercular agents: a systematic review and meta-analysis (protocol)

DiscussionOur review and meta-analysis will update and add to the existing research in this field. By not restricting the scope of the review to a specific drug, genetic variant, or toxicity outcome, we hope to synthesise data for associations between genetic variants and anti-tuberculosis drug-related toxicity outcomes that have previously not been summarised in systematic reviews, and consequently, add to the knowledge base of the pharmacogenetics of anti-tuberculosis drugs.Systematic review registrationPROSPERO CRD42017068448
Source: Systematic Reviews - Category: International Medicine & Public Health Source Type: research