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Effect of acupuncture on the endoplasmic reticulum stress IRE1-CHOP pathway and the expression levels of Bax and Bcl-2 protein as well as genes in pancreatic tissue of rats with diabetes mellitus

Conclusion There was endoplasmic reticulum stress in the pancreatic tissue of rats with STZ-induced diabetes mellitus, and IRE 1-CHOP signal pathway was the main pathway for inhibiting the endoplasmic reticulum stress in the pancreatic tissue. Acupuncture can improve the endoplasmic reticulum stress in pancreatic tissue, inhibit apoptosis genes, and protect the pancreatic tissue through IRE 1-CHOP signal pathway.
Source: World Journal of Acupuncture Moxibustion - Category: Complementary Medicine Source Type: research

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CONCLUSION: EA at Weiwanxiashu and BL15 had differential effects on metabolic markers in the STZ-induced rat model of DM. These effects may be explained neuroanatomically by variations in the segmental innervation of the tissues at these locations. PMID: 28751464 [PubMed - as supplied by publisher]
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - Category: Complementary Medicine Authors: Tags: Acupunct Med Source Type: research
Conclusion The result of this study suggests that 30 minutes of needling at CV-12 might be useful in reducing blood glucose level in patients with T2DM.
Source: Journal of Acupuncture and Meridian Studies - Category: Complementary Medicine Source Type: research
DiscussionThe aim of this study is to evaluate the efficacy and safety of acupuncture paired with herbal medicine for the treatment of patients with prediabetes.Trial registrationChinese clinical trials registerChiCTR-INR-16008891. Registered on 23 July 2016.
Source: Trials - Category: Research Source Type: clinical trials
Publication date: Available online 18 May 2017 Source:Journal of Acupuncture and Meridian Studies Author(s): Yun Jin Kim Myasthenia gravis (MG) is an acquired disease of the neuromuscular junctions characterized by muscular weakness and fatigue, with a prevalence of 50–125 cases per million population in western countries. In men, it usually appears after the age of 60 years, while in women, it usually appears before the age of 40 years. Long-term immunosuppression with corticosteroids is the mainstay treatment for patients with MG; however, the use of corticosteroids is a well-documented risk factor for t...
Source: Journal of Acupuncture and Meridian Studies - Category: Complementary Medicine Source Type: research
Publication date: Available online 18 May 2017 Source:Journal of Acupuncture and Meridian Studies Author(s): Yun Jin Kim Myasthenia Gravis is an acquired disease of the neuromuscular junction characterized by muscular weakness and fatigue, with a prevalence of 50 to 125 cases per million population in Western countries. In males, it usually appears after the age of 60 while in females, it usually appears before the age of 40. Long-term immunosuppression with corticosteroids is the mainstay treatment for patients with myasthenia gravis; however, the use of corticosteroids is a well-documented risk factor of Type 2 diabetes...
Source: Journal of Acupuncture and Meridian Studies - Category: Complementary Medicine Source Type: research
Conclusion The electroacupuncture at ear and body acupoints can reduce the instant fasting blood glucose of T2DM machins apparently. There is time effect on instant fasting blood glucose of T2DM machins treated by electroacupuncture. The efficacy of 30-minute stimulation is superior to that of 15-minute acupuncture. After acupuncture continuously for 4 days, the effect is better than that with acupuncture for 3 days successively.
Source: World Journal of Acupuncture Moxibustion - Category: Complementary Medicine Source Type: research
Publication date: Available online 16 December 2016 Source:Journal of Acupuncture and Meridian Studies Author(s): Fitrullah, Addison Rousdy Diabetes mellitus is a dangerous disease worldwide. Indonesia has 10 million diabetics and 17.9 million pre-diabetics. Unfortunately, less than half of diabetics are aware of their conditions and less than one percent of those receiving medical treatment achieve their healing targets. Because acupressure is believed to be an effective treatment without the use of drugs, this research investigated acupressure as a comfortable and effective way of treating patients with diabetes mellitu...
Source: Journal of Acupuncture and Meridian Studies - Category: Complementary Medicine Source Type: research
Conclusion The result of this study suggests that although 20-minutes of needling at CV-12 without stimulation produce mild reduction in RBG levels in healthy volunteers it did not produce a statistically significant result.
Source: Journal of Acupuncture and Meridian Studies - Category: Complementary Medicine Source Type: research
We present a case of a 65-year-old man whom presented with right-sided body weakness. He had a past medical history of uncontrolled diabetes mellitus, hypertension, and obstructive sleep apnea requiring his using a nasal continuous positive airway pressure (CPAP) device during sleep. We performed a computed tomography (CT) brain scan; it revealed a left-sided acute on chronic subdural hemorrhage. Due to his multiple co-morbidities, we decided to perform the surgical procedure under electroacupuncture anesthesia. The aim of this case report is to describe a craniotomy performed under electroacupuncture on an elderly patient...
Source: Journal of Acupuncture and Meridian Studies - Category: Complementary Medicine Source Type: research
Abstract Painful diabetic peripheral neuropathy occurs in approximately 25% of patients with diabetes mellitus who are treated in the office setting and significantly affects quality of life. It typically causes burning pain, paresthesias, and numbness in a stocking-glove pattern that progresses proximally from the feet and hands. Clinicians should carefully consider the patient's goals and functional status and potential adverse effects of medication when choosing a treatment for painful diabetic peripheral neuropathy. Pregabalin and duloxetine are the only medications approved by the U.S. Food and Drug Administr...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
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