[Acute fatty liver of pregnancy and mitochondrial fatty acid oxidation. Consequences for the offspring].

[Acute fatty liver of pregnancy and mitochondrial fatty acid oxidation. Consequences for the offspring]. Arch Pediatr. 2017 Jun 21;: Authors: Anon B, Barbet C, Gendrot C, Labarthe F, Bacq Y Abstract Acute fatty liver of pregnancy (AFLP) is a rare liver disease unique to pregnancy that can lead to acute liver failure. The prognosis, initially often fatal for both mother and child, has been improved by prompt delivery. The diagnosis should be highly suspected if the mother presents epigastric pain, nausea and/or vomiting, or polyuria-polydipsia in the third trimester of pregnancy. AFLP has been found associated with a genetic deficiency of fatty acid beta-oxidation, which may cause sudden death in infancy. Consequently, the mother and her newborn should undergo screening for this deficiency. PMID: 28647472 [PubMed - as supplied by publisher]
Source: Archives de Pediatrie - Category: Pediatrics Authors: Tags: Arch Pediatr Source Type: research