Radiation and PD-1 inhibition: Favorable outcomes after brain-directed radiation

Patients with metastatic melanoma, renal cell carcinoma (RCC) and non-small cell lung cancer (NSCLC) are increasingly treated with immune checkpoint blockade targeting the programed death (PD)-1 receptor, often with palliative radiation therapy. Outcome data are limited in this population.

Source: Radiotherapy and Oncology - June 26, 2017 Category: Radiology Authors: Luke R.G. Pike, Andrew Bang, Patrick Ott, Tracy Balboni, Allison Taylor, Paul Catalano, Bhupendra Rawal, Alexander Spektor, Monica Krishnan, Daniel Cagney, Brian Alexander, Ayal A Aizer, Elizabeth Buchbinder, Mark Awad, Leena Gandhi, F. Stephen Hodi, Jona Tags: Original article Source Type: research