The Bio-Psycho-Social Dimension In Women's Sexual Desire: 'Argumentum Ad Novitatem'.

The Bio-Psycho-Social Dimension In Women's Sexual Desire: 'Argumentum Ad Novitatem'. Curr Drug Targets. 2017 Jun 21;: Authors: Roslan NS, Jaafar NRN, Sidi H, Baharuddin N, Kumar J, Das S, Hussein NHN Abstract Sexual desire includes complex motivation and drive. In the context of biological and cognitive-emotive state art of science, it is often a neglected field in medicine. With regard to the treatment, study on women's sexual function received less attention compared to the men's sexuality. In the past, this endeavor was relatively not well disseminated in the scientific community. Recently, there was a revolutionized surge of drug targets available to treat women with low sexual desire. It is timely to review the relevant biological approach, especially in the context of pharmacotherapy to understand this interesting clinical entity which was modulated by numerous interactive psychosocial inter-play and factors. The complex inter-play between numerous dimensional factors lends insights to understand the neural mechanism, i.e. the rewards centre pathway and its interaction with external psychosocial stimulus, i.e. relationship and meaningful life events. The role of hormones i.e. oxytocin and testosterone regulation and neurotransmitters i.e. dopamine and serotonin modulation was pivotal as reflected by the introduction of a molecule of flibanserin, a full agonist of the 5-HT1A and partial agonist of D4 to treat pre-menopausal wome...
Source: Current Drug Targets - Category: Drugs & Pharmacology Authors: Tags: Curr Drug Targets Source Type: research