Molecules, Vol. 22, Pages 969: Docosahexaenoic Acid Induces Expression of Heme Oxygenase-1 and NAD(P)H:quinone Oxidoreductase through Activation of Nrf2 in Human Mammary Epithelial Cells

In conclusion, DHA activates Nrf2, possibly through modification of critical Keap1 cysteine 288 residue and PKCδ-mediated phosphorylation of Nrf2, leading to upregulation of HO-1 and NQO1 expression.

Source: Molecules - June 10, 2017 Category: Chemistry Authors: Hye-Yoon Bang Sin-Aye Park Soma Saeidi Hye-Kyung Na Young-Joon Surh Tags: Article Source Type: research