Deletion of one allele of Mthfd1 (methylenetetrahydrofolate dehydrogenase 1) impairs learning in mice.
In this study, we evaluated cognitive function in Mthfd1(gt/+) male and female mice using a behavioral battery composed of eight different tests. We found that these mice display impaired cue-conditioned learning, while other behaviors remain intact.
PMID: 28559181 [PubMed - as supplied by publisher]
Source: Behavioural Brain Research - Category: Neurology Authors: Pjetri E, Zeisel SH Tags: Behav Brain Res Source Type: research
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