Effect of a long-term intensive lifestyle intervention on prevalence of cognitive impairment

Conclusions: Ten years of behavioral weight loss intervention did not result in an overall difference in the prevalence of cognitive impairment among overweight or obese adults with type 2 diabetes. Clinicaltrials.gov identifier: NCT00017953 (Action for Health in Diabetes). Level of evidence: This study provides Class II evidence that for overweight adults with type 2 diabetes, a lifestyle intervention designed to reduce weight and increase physical activity does not lower the risk of cognitive impairment.

http://www.neurology.org/cgi/content/short/88/21/2026?rss=1

Source: Neurology - May 22, 2017 Category: Neurology Authors: Espeland, M. A., Luchsinger, J. A., Baker, L. D., Neiberg, R., Kahn, S. E., Arnold, S. E., Wing, R. R., Blackburn, G. L., Bray, G., Evans, M., Hazuda, H. P., Jeffery, R. W., Wilson, V. M., Clark, J. M., Coday, M., Demos-McDermott, K., Foreyt, J. P., Green Tags: All Clinical trials, All Cognitive Disorders/Dementia ARTICLE Source Type: research