Clinical trial discovers a new way to prevent children with arthritis and eye disease losing their sight

This study demonstrates the benefit of adalimumab in children with uveitis. This is the first randomised trial of its kind worldwide and the results will have a major impact in children with uveitis all around the world."Finding the best way of caring for children with arthritis and uveitisProfessor Beresford from University of Liverpool and Alder Hey Children’s NHS Foundation Trust said: "This landmark trial has demonstrated the commitment and leadership of colleagues across the UK in working closely with patients and parents in tackling a key priority of finding the very best way of caring for children with arthritis and this serious problem of uveitis."It has shown the UK to be extremely well placed to deliver challenging trials in children, with the support of the NIHR Clinical Research Network and other research networks that are in place across the UK."There are 15,000 children and adolescents in the UK with the auto-immune disease JIA. One third of those are likely to develop uveitis, leading to more serious visual impairments and may be registered as blind. Stephen Simpson, director of research and programmes at Arthritis Research UK, said: "We're thrilled of the outcome of this trial and the huge promise it heralds for transforming the quality of life for the large numbers of children with JIA-associated uveitis."This trial is an impressive example of how investing in exceptional science can ultimately help change how treatment is delivered with direct and imme...
Source: Arthritis Research UK - Category: Rheumatology Source Type: news