Meet the girl who has had four hearts – video
Born with a serious heart condition called dilated cardiomyopathy, Chloe Narbonne had five major operations – and four hearts – by the age of 12. She defied the odds to become the youngest person in Europe to receive an artificial heart thanks to groundbreaking surgery involving 30 NHS staff. Now Chloe, her mother and medical personnel tell her amazing story for the first timeContinue reading...
Functional mitral regurgitation (FMR) in non-ischemic cardiomyopathy (NICM) may be partly related to the dysfunction of subvalvular apparatus. Thus, we sought to investigate the correlation between papillary muscle viability and FMR changes in NICM.
Patients with dilated cardiomyopathy (DCM) who achieved left ventricular reverse remodeling (LVRR) have a favorable prognosis, but it is still difficult to precisely predict LVRR in the clinical setting.
The underlying mechanisms of right ventricular (RV) dysfunction in patients with non-ischemic dilated cardiomyopathy (NICM) remain poorly defined. We evaluated a potential correlation between local mechanical dyssynhcrony of interventricular septum (IVS) and RV function in these patients.
We reported the effect of CF VAD in small children with dilated cardiomyopathy refractory to conventional pharmacological treatment.
Danon Disease (DD) is a rare X-linked disorder due to mutations in the Lysosomal Associated Membrane Protein 2 (LAMP-2) gene. Patients present with cardiac manifestations of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM). The goal of this study is to characterize the longitudinal progression of hypertrophic phenotypes and descriptions of left ventricular strain in DD.
Heart failure (HF) affects more than 6 million adults in the U.S and is associated with significant morbidity and mortality. The majority of HF patients suffer from either ischemic (ICM) or dilated (DCM) cardiomyopathy. Little is known about the genetic alterations in DCM or ICM patients. Therefore, our aim was to characterize differentially expressed genes in left ventricular tissue from DCM and ICM patients.
Myocarditis is a known etiology of both acute fulminant heart failure and chronic dilated cardiomyopathy requiring heart transplantation. We sought to evaluate the long-term post-transplant outcomes of pts with myocarditis.
We aim to evaluate clinical outcomes, echocardiographic changes, heart rate (HR) modifications and side effects in children with dilated cardiomyopathy (DCM) and chronic heart failure (HF) treated by high dosage of carvedilol.
Dilated cardiomyopathy (DCM) is a common cause of advanced heart failure (HF) in children and the risk of sudden death in DCM is not well defined although population-based studies have described risk factors like older age, familial DCM and lower fractional shortening. Myocardial fibrosis as assessed by late gadolinium enhancement (LGE) on 3-T cardiac magnetic resonance imaging (CMR) is well known to be associated with adverse events in DCM. We sought to assess the conditional survival (CS) of children and adolescents with DCM and advanced HF based on native T1 mapping (combined proton signal from myocytes and interstitium...
This study aimed to report the long‐term outcomes and clinical management following LVAD explantation.Methods and resultsAn analysis of the European Registry for Patients with Mechanical Circulatory Support was performed to identify all adult patients with myocardial recovery and successful explantation. Pre ‐implant characteristics were retrieved and compared with the non‐recovery patients. The follow‐up data after explantation were collected via a questionnaire. A Kaplan–Meier analysis for freedom of the composite endpoint of death, heart transplantation, LVAD reimplantion, or heart failure (H F) relapse wa...