Cardio-protective effects of phytosterol-enriched functional black tea in mild hypercholesterolemia subjects

Publication date: April 2017 Source:Journal of Functional Foods, Volume 31 Author(s): Asım Orem, Cesarettin Alasalvar, Birgül Vanizor Kural, Serap Yaman, Cihan Orem, Ayse Karadag, Ebru Pelvan, Jerzy Zawistowski Hypercholesterolemia is a common condition in which the risk for the development of cardiovascular disease (CVD) is increased. Due to their hypocholesterolemic effects, phytosterols are considered to be effective in the prevention of CVD, particularly coronary heart disease. The aim of study was to investigate the cardio-protective effects of phytosterol-enriched instant black tea (functional black tea) in subjects with mild hypercholesterolemia. A randomized, double-blind, and placebo-controlled study was conducted on volunteer subjects aged 25–60y with mild hypercholesterolemia [plasma total cholesterol concentrations 200–239mg/dL (5.2–6.2mmol/L)]. Subjects were randomly divided into placebo (PBO) (n =33; M/F, 23/10), instant black tea (IBT) (n =34; M/F, 25/9), and functional black tea (FBT) (2g phytosterols/d) (n =32; M/F, 24/8) groups and intervention period was conducted for 4wk. Compared with baseline, consumption of FBT significantly decreased the concentrations of total cholesterol by 5.6% (P <0.001), low-density lipoprotein (LDL) cholesterol by 8.7% (P <0.001), apolipoprotein B (P <0.05), and oxidative stress index (P <0.05), while increasing the concentrations of adiponectin, total antioxidant status, and tissue-p...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research