The Nephroprotective Effect of Folic Acid

In this study, Xu et al demonstrated that low-dose folic acid treatment in addition to enalapril in patients with hypertension without prior cardiovascular events reduced the incidence and progression of chronic kidney disease (CKD) compared with treatment with enalapril alone. Although the mechanism of this effect remains to be proven, decreases in plasma homocysteine are a potential explanation.
Source: JAMA Internal Medicine - Category: Internal Medicine Source Type: research