The neuronal transcription factor NPAS4 is a strong inducer of sprouting angiogenesis and tip cell formation

Conclusions
NPAS4 is expressed in endothelial cells, regulates VE-cadherin expression and regulates sprouting angiogenesis.

Source: Cardiovascular Research - January 22, 2017 Category: Cardiology Authors: Esser, J. S., Charlet, A., Schmidt, M., Heck, S., Allen, A., Lother, A., Epting, D., Patterson, C., Bode, C., Moser, M. Tags: Vascular biology Source Type: research