When It’s More Than the Winter Blues
By Stacy Simon The gifts have been opened, the holiday meals eaten, the visitors gone home, and the decorations put away for another year. As the fun and festivities become memories, this is the time of year many people feel a little let down or sad. Treating yourself to a movie, spending time with friends, doing volunteer work, or participating in physical activities you enjoy can help you cheer up and regain your emotional balance. RESOURCES: Depression in cancer patients But for some people, it isn’t that easy. Sadness that doesn’t go away or keeps you from enjoying things you usually like could be a sign of clinical depression. One type of clinical depression, seasonal affective disorder (SAD), is more common around this time of year when the days are shorter and the nights are longer. Treatment for SAD usually involves light therapy, and can also include talk therapy or prescription medication. Other kinds of clinical depression may be caused by a tragic event, a period of stress, an illness, changes in the brain that affect mood, or for reasons that nobody understands. Getting help is important, because treatment, including medicines, counseling, or a combination of both, can reduce the suffering that comes along with depression and improve quality of life. What to Look for Ongoing sad or “empty” mood for most of the day Loss of interest or pleasure in almost all activities most of the time Major weight loss (when not dieting) or weight gain...
Conclusion: Our case report underlines the importance of active endoscopic surveillance of the remaining colon and rectum in patients with diverting stomas and inflammatory bowel disease in order to detect stenosis. If endoscopic control is not possible due to obliteration, surgical therapy must be discussed due to the risk of developing cancer.Case Rep Gastroenterol 2018;12:143 –146
Conclusions: This study is the first nationwide study presenting an increase in incidence of EP-NEC patients from 196 to 260 cases annually in the Netherlands. We found the best 5 year relative survival to be for EP-NEC patients with local disease located in the bladder, where the worst 5 year relative survival was found in the oesophagus.
DEMENTIA can be a stressful and costly process for all those involved, so it is important to know what type of dementia is affecting the person with the condition. Dementia with Lewy Bodies is one of them.
Karine A. Al Feghali, Rami A. Ballout, Assem M. Khamis, Elie A. Akl, Fady B. Geara
Mayra A. Carrillo, Anjie Zhen, Scott G. Kitchen
PROSTATE cancer symptoms can be hard to spot, especially in the early stages. As it progresses, signs of the disease can begin to show, and if the cancer grows outside of the prostate, and other symptoms can develop, including three related to sex.
CONCLUSIONS Our results suggest that gastric cancer cells induce the transition of pericytes to CAFs by exosomes-mediated BMP transfer and PI3K/AKT and MEK/ERK pathway activation, and suggest that pericytes may be an important source of CAFs. PMID: 29668670 [PubMed - in process]
CONCLUSIONS This study is the first to provide evidence that propofol-mediated autophagy regulation is an underlying part of the mechanism by which propofol regulates HeLa cells progression. PMID: 29667627 [PubMed - in process]
CONCLUSIONS The skin microdialysis study indicated PAE-LCNPs have good transdermal permeability and efficacy. Pharmacological experiments based on the study found that the topical pigmentation model of guinea pigs showed a better therapeutic effect. PMID: 29666359 [PubMed - in process]