When It’s More Than the Winter Blues
By Stacy Simon The gifts have been opened, the holiday meals eaten, the visitors gone home, and the decorations put away for another year. As the fun and festivities become memories, this is the time of year many people feel a little let down or sad. Treating yourself to a movie, spending time with friends, doing volunteer work, or participating in physical activities you enjoy can help you cheer up and regain your emotional balance. RESOURCES: Depression in cancer patients But for some people, it isn’t that easy. Sadness that doesn’t go away or keeps you from enjoying things you usually like could be a sign of clinical depression. One type of clinical depression, seasonal affective disorder (SAD), is more common around this time of year when the days are shorter and the nights are longer. Treatment for SAD usually involves light therapy, and can also include talk therapy or prescription medication. Other kinds of clinical depression may be caused by a tragic event, a period of stress, an illness, changes in the brain that affect mood, or for reasons that nobody understands. Getting help is important, because treatment, including medicines, counseling, or a combination of both, can reduce the suffering that comes along with depression and improve quality of life. What to Look for Ongoing sad or “empty” mood for most of the day Loss of interest or pleasure in almost all activities most of the time Major weight loss (when not dieting) or weight gain...
Conclusions: The use of mHealth for obese adults showed a modest short-term effect on body weight and BMI. Although the weight loss associated with mHealth did not meet the recommendation of the Scottish Intercollegiate Guideline Network, which considers a reduction of approximately 5 to 10 kg of the initial body weight as a successful intervention. Well-designed RCTs are needed to reveal the effects of mHealth interventions. PMID: 30788177 [PubMed]
The American Society of Anesthesiologists (ASA) standards were updated in 2011 to recommend end-tidal carbon dioxide (EtCO2) monitoring during moderate sedation, which is now common practice in IR. Studies show EtCO2 monitoring improves detection of respiratory depression and hypoxemia. The purpose of this study was to evaluate the incidence of respiratory depression and hypoxemia from oversedation during IR procedures before and after implementation of EtCO2 monitoring.
The objective of the present work was to formulate slow- and sustained-release octreotide acetate-loaded PLA/PLGA (polylactide)(poly (Lactic-co- Glycolic) acid) microspheres and prospectively test the effects of catheter-directed gastric artery administration of these microspheres on plasma ghrelin levels and body weight in swine. Octreotide is a long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. In the GI system it inhibits secretin, gastrin, vasoactive intestinal peptide, motilin and ghrelin.
The objective of this compound is to decrease the rate of rectal toxicity related to radiation therapy, by creating a gap between the prostate and rectum. Secondary benefits include decreased urinary complications and improved sexual quality of life. The hydrogel spacer maintains space for approximately 3 months, and is absorbed in about 6 months.
To evaluate the efficacy and clinical impact of 3 Tesla in-bore trans-rectal magnetic resonance-guided biopsy (3T MRGB) for prostate cancer (PCa) detection based on PIRADSv2 in patients with either suspected prostate cancer or under active surveillance.
We describe our experience using MRI fused CBCT guidance for prostate biopsy. There are no published reports on the use of CBCT guidance in prostate biopsies. We hypothesize this technique will have an adequate safety profile while accurately detecting prostate cancer.
Image-guided thermal ablation has become the standard of care for treating early stage liver cancer. However, a significant limitation to a successful ablation procedure is the heat-sink effect, which may lead to suboptimal thermal dose delivery. Currently, there is no reliable method for quantifying the heat-sink effect due to limited information on blood vessel flow and its associated anatomy relative to the ablation zone. The purpose of this study was to use 4D-flow MRI to map out liver flow patterns and correlate flow rates with ablation zone volumes.
Biphenotypic hepatocellular-cholangiocarcinoma (HCC-CC) is a rare type of primary liver cancer that carries a poor prognosis. Since most patients present at a stage too advanced for surgical resection, loco-regional liver directed therapy is often performed for palliative or downstaging purposes. The purpose of this study is to evaluate patient outcomes after Yttrium-90 radioembolization (Y90) in patients with HCC-CC.
Immunotherapy is a paradigm-shifting advance in cancer care, but the overall response rates remain low. There has been a renaissance in the concept of promoting the immune-responsiveness of the tumor immune microenvironment via intratumoral (IT) delivery of immunostimulatory agents. However, the optimal method for IT delivery of such medications that maximizes IT dispersion while minimizing perilesional leakage and systemic distribution is unknown. The purpose of this study was to characterize IT drug distribution and its influence on drug efficacy using conventional end-hole needles (EHNs) versus multi-sidehole needles (MSHN).
Ports and gastrostomy/gastrojejunostomy tubes (G/GJ-tubes) are common devices utilized during treatment of oncology patients. Combining port and G/GJ-tube placement into a single session can be advantageous from both patient care and resource utilization perspectives. We compared the rates of infection and other device complications in patients receiving a port and G/GJ-tube in one session compared with receiving the devices in two sessions.