Angina and Future Cardiovascular Events in Stable Patients With Coronary Artery Disease: Insights From the Reduction of Atherothrombosis for Continued Health (REACH) Registry [Coronary Heart Disease]

BackgroundThe extent to which angina is associated with future cardiovascular events in patients with coronary artery disease has long been debated.Methods and ResultsIncluded were outpatients with established coronary artery disease who were enrolled in the REACH registry and were followed for 4 years. Angina at baseline was defined as necessitating episodic or permanent antianginal treatment. The primary end point was the composite of cardiovascular death, myocardial infarction, or stroke. Secondary end points included heart failure, cardiovascular hospitalizations, and coronary revascularization. The independent association between angina and first/total events was examined using Cox and logistic regression models. Out of 26 159 patients with established coronary artery disease, 13 619 (52%) had angina at baseline. Compared with patients without angina, patients with angina were more likely to be older, female, and had more heart failure and polyvascular disease (P

Source: JAHA:Journal of the American Heart Association - September 27, 2016 Category: Cardiology Authors: Eisen, A., Bhatt, D. L., Steg, P. G., Eagle, K. A., Goto, S., Guo, J., Smith, S. C., Ohman, E. M., Scirica, B. M., the REACH Registry Investigators Tags: Myocardial Infarction, Angina, Coronary Artery Disease Original Research Source Type: research