Network-based expression analysis reveals key genes related to glucocorticoid resistance in infant acute lymphoblastic leukemia

ConclusionsFrom our data we conclude that available systems biology approaches can be employed to detect new candidate genes that may provide further insights into drug resistance ofMLL-rearranged infant ALL cases. Such approaches complement conventional gene-wise approaches by taking putative functional interactions between genes into account.
Source: Cellular Oncology - Category: Cancer & Oncology Source Type: research