Posterior reversible encephalopathy syndrome in a patient of organophosphate poisoning

Rajesh Phatake, Sameer Desai, Manikanth Lodaya, Shrinivas Deshpande, Nagaraj TankasaliIndian Journal of Critical Care Medicine 2014 18(4):250-252A 32-year-old male presented with a history of consuming some organophosphorous compound with suicidal intention.He was treated with atropine, pralidoxime, ventilator support. During stay patient had persistent irritability, tachycardiaand hypertension despite sedation and labetalol infusion. He developed headache, visual blurring hemiparesis and focal seizures. Magnetic resonance imaging of the brain revealed multifocal hyperintensities mainly in subcortical areas of parietal and occipital regions in T2-weighted images, with increased values of Apparent Diffusion Coefficient, suggesting posterior reversible encephalopathy syndrome (PRES). The possibilities of PRES caused by organophosphorous poisoning either due to hypertension caused by autonomic deregulation or direct neurological toxicity has been discussed.
Source: Indian Journal of Critical Care Medicine - Category: Intensive Care Authors: Source Type: research